VNNL1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VNNL1_DROME
• UniProt AC: Q9NFP1
• Protein Name: Vanin-like protein 1
• Gene Name: vanin-like
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 558
• Protein Description: Probable hydrolase..
• Protein Sequence: MSNTWWWLSVVLLILGLMPGMSQQAALAESDYYTAGVVEFKQSILSLSAWSDSLAGYVEIINSENASATDIIVFPESTLNSAGSTTFVPNPEDQINPCLSDPNATYYEEFLVTLSCAARNASKYIVINLTEKQKCEDIPEDTRPCASNGLNVFNTNVVFDRQGVVVSRYRKVHLYGEAKNSTFLPELITFETDFGVTFGHFICFDILFYTPAHQLIVEQGITDFVYPAMWFSQLPFLTAVQTQQGWAYANDVNLLASGASRPSIGNSGSGIYHGRSGTLTSVMRQDSGERAIYVAQVPKYTRSRSLKKRAKRSLQEIQTRQVASSSSFYMKRDYVENYESELLKLDEGTSGAINRTICQGSFCCNFDIAWRSLGTATENGSYYSYRLGTYDGWRNENNVDANYIRNCALFTCSGDSIDDCGKLLPTEGELQQSRVTFTRLAIGVTYPESREFLLFPDTLQDSLLPLEPSQFEWSQRKPTEDSYVQEVRFALKETQELSNLLTFGIYGNYYDNECTFGVGTEEEQLACGYRSGSPGLRILGGWLAMPLIILAIARTMSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
65	N-linked_Glycosylation	VEIINSENASATDII EEEECCCCCCCCEEE	38.73	-
103	N-linked_Glycosylation	NPCLSDPNATYYEEF CCCCCCCCCCCHHHH	50.32	-
120	N-linked_Glycosylation	TLSCAARNASKYIVI HHHHHHHCCCEEEEE	43.79	-
128	N-linked_Glycosylation	ASKYIVINLTEKQKC CCEEEEEECCCHHCC	29.98	-
180	N-linked_Glycosylation	HLYGEAKNSTFLPEL EEECCCCCCCCCCCE	54.02	-
354	N-linked_Glycosylation	EGTSGAINRTICQGS CCCCCCCCCEEECCC	34.21	17893096
379	N-linked_Glycosylation	SLGTATENGSYYSYR ECCCCCCCCCEEEEE	40.11	-
531	GPI-anchor	QLACGYRSGSPGLRI HHHHCCCCCCCCCEE	34.83	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VNNL1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VNNL1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VNNL1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

N-linked Glycosylation

"Identification of N-glycosylated proteins from the central nervoussystem of Drosophila melanogaster.";
Koles K., Lim J.-M., Aoki K., Porterfield M., Tiemeyer M., Wells L.,Panin V.;
Glycobiology 17:1388-1403(2007).
Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-354, AND MASSSPECTROMETRY.
PubMed: 17893096