VILL_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VILL_MOUSE
• UniProt AC: Q91YD6
• Protein Name: Villin-like protein
• Gene Name: Vill {ECO:0000312|MGI:MGI:1201781}
• Organism: Mus musculus (Mouse).
• Sequence Length: 859
• Protein Description: Possible tumor suppressor..
• Protein Sequence: MDINQDLPAIDSHRALQIWITENLKMLPLPERAHGNFFEECCYVVLHVPQSPKATQGGSSDLHYWIGKDASAEAREAAVSFVQCLQEDLGDQTVLHRESQGHESDCFHSYFHPGVIYRKGGRDSALKFAETNMYNVQRLLHIKGRKHVSATEVALSWNSFNKGDIFLLDLGKVMIQWNGPKASISEKARALTLTCNLRDRERGGRAQIAVVDAENEATNLLRIMEAVLGCRSGSLCPSVPSNSVSQLQKANVRLYHVCEKGTDLVVQELATRPLTQDLLQEDGCYLLDQGGFKIYMWQGRKSSPQEKKAALSRAVGFIQAKGYPNYTNVEVVNDGAESTAFQQLFWSWSKELDRKKHPEKSKLVQGNLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQDLQRQPVHPKYYGQLCSGNCYLVLYTYQKLGCVQYLLYLWQGHQSTVEDTKALNCSAEELDLMHQGALAQGHVTMGSEPPHFLAIFQGRLVVFQGNAGNKGERPPVSDTRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLITSHVCYLWFGKGCHGDQREMARTVVSVFPGNNKETVLEGQEPLYFWEALGGRAPYPSNKRLPEEVWSIQPRLFECSSHAGCLVLTEVLFFGQEDLDKYDIMLLDTCQEIFLWLGEAAGEWKKEAVAWGLEYLRTHPAERSLATPIFVVKQGHEPATFTGWFVTWDPYKWMNSQSYEEMVGNSLGPGSAISEMTAEVHNFQLTPRLSDNKAGHPALQAFKGSQDSPENELGLDLRVDGANPSMNHTSSCSDSMVNGSLPRERLMHQALEDLPPGVDPARKEFYLSDSDFQDIFGKSKEEFYSMAKWKQQQAKKKLGFF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
181	Ubiquitination	MIQWNGPKASISEKA EEEECCCCCCHHHHH	57.05	-
232	Phosphorylation	EAVLGCRSGSLCPSV HHHHCCCCCCCCCCC	36.49	26239621
234	Phosphorylation	VLGCRSGSLCPSVPS HHCCCCCCCCCCCCC	28.22	26239621
238	Phosphorylation	RSGSLCPSVPSNSVS CCCCCCCCCCCCCHH	45.74	23984901
751	Ubiquitination	TPRLSDNKAGHPALQ CCCCCCCCCCCHHHH	61.81	-
761	Malonylation	HPALQAFKGSQDSPE CHHHHHHCCCCCCCC	61.75	26073543
763	Phosphorylation	ALQAFKGSQDSPENE HHHHHCCCCCCCCCC	31.25	29550500
766	Phosphorylation	AFKGSQDSPENELGL HHCCCCCCCCCCCCC	26.86	26239621

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VILL_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VILL_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VILL_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of VILL_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.