VIL2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VIL2_ARATH
• UniProt AC: Q9SUM4
• Protein Name: VIN3-like protein 2
• Gene Name: VIL2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 714
• Subcellular Localization: Nucleus. Probably DNA-associated..
• Protein Description: Maybe involved in both the vernalization and photoperiod pathways by regulating gene expression. Binds preferentially to dimethylated histone H3 'Lys-9' (H3K9me2). Promotes flowering in non-inductive photoperiods (e.g. short days) through the maintenance of the epigenetically repressed state of MAF5 via H3K9me2 and plant homeodomain / polycomb repressive complex 2 (PHD-PRC2)-dependent H3K27me3..
• Protein Sequence: MDSSLDGAAGDSSKCSEMSVDEKRQLVYELSKQSHLAAEVLQAWSRQEILQILCAEMGKERKYTGLTKVKIIETLLKIVSEKNSGECEGKKRDSDCLPIQRNTKRQRKVDNPSRYVIPATNIVTSNNASGSCSSVNTKGESTTIYCKNLACRAVLRQEDSFCRRCSCCICRKYDDNKDPSLWLTCSSDPPFEGESCGFSCHLECAFNTEKSGLGKDKQSEGCCFYCVSCGKANSLLECWKKQLTIAKETRRVEVLCYRLFLVQKLLKSSTKYRNLCEVVDEAVKTLEADVGPLTGLPMKMGRGIVNRLHSGPDVQKLCSSALESLETIATTPPDVAALPSPRSSKMQQDCSYVLSNEISADTATTGSTKIRFEDVNATSLTVVLASNEIPSPPNIVHYSIWHRKVPEKDYPEKSTCTLFIPNTRFVVSGLAPASEYCFKVVSYSGTREMGVDEINVLTRSAEEGANCSSAVERSVSPLTNCSTLSSNPSSVEAESNNDYIVPKKPSSKNEDNNSPSVDESAAKRMKRTTDSDIVQIEKDVEQIVLLDDEEQEAVLDKTESETPVVVTTKSLVGNRNSSDASLPITPFRSDEIKNRQARIEISMKDNCNNGDHSANGGTESGLEHCVKIIRQLECSGHIDKNFRQKFLTWYSLRATSQEIRVVKIFIDTFIDDPMALAEQLIDTFDDRVSIKRSAVGGSGASAVVPSGFCMKLWH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MDSSLDGAAG -----CCCCCCCCCC		25561503
4	Phosphorylation	----MDSSLDGAAGD ----CCCCCCCCCCC		25561503
340	Phosphorylation	PDVAALPSPRSSKMQ CCHHHCCCCCCCHHH		30291188
514	Phosphorylation	SKNEDNNSPSVDESA CCCCCCCCCCCCHHH		27531888
516	Phosphorylation	NEDNNSPSVDESAAK CCCCCCCCCCHHHHH		30407730
577	Phosphorylation	SLVGNRNSSDASLPI CCCCCCCCCCCCCCC		23776212
578	Phosphorylation	LVGNRNSSDASLPIT CCCCCCCCCCCCCCC		23776212
581	Phosphorylation	NRNSSDASLPITPFR CCCCCCCCCCCCCCC		23776212
585	Phosphorylation	SDASLPITPFRSDEI CCCCCCCCCCCCHHH		23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VIL2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VIL2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VIL2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of VIL2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.