VGLL2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VGLL2_HUMAN
• UniProt AC: Q8N8G2
• Protein Name: Transcription cofactor vestigial-like protein 2
• Gene Name: VGLL2
• Organism: Homo sapiens (Human).
• Sequence Length: 317
• Subcellular Localization: Nucleus.
• Protein Description: May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles..
• Protein Sequence: MSCLDVMYQVYGPPQPYFAAAYTPYHQKLAYYSKMQEAQECNASPSSSGSGSSSFSSQTPASIKEEEGSPEKERPPEAEYINSRCVLFTYFQGDISSVVDEHFSRALSQPSSYSPSCTSSKAPRSSGPWRDCSFPMSQRSFPASFWNSAYQAPVPPPLGSPLATAHSELPFAAADPYSPAALHGHLHQGATEPWHHAHPHHAHPHHPYALGGALGAQAAPYPRPAAVHEVYAPHFDPRYGPLLMPAASGRPARLATAPAPAPGSPPCELSGKGEPAGAAWAGPGGPFASPSGDVAQGLGLSVDSARRYSLCGASLLS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSCLDVMYQ ------CCHHHHHHH	24.32	24043423
8	Phosphorylation	MSCLDVMYQVYGPPQ CCHHHHHHHHHCCCC	8.48	24043423
11	Phosphorylation	LDVMYQVYGPPQPYF HHHHHHHHCCCCCCC	14.37	24043423
17	Phosphorylation	VYGPPQPYFAAAYTP HHCCCCCCCEEECCH	10.70	24043423
22	Phosphorylation	QPYFAAAYTPYHQKL CCCCEEECCHHHHHH	11.97	24043423
23	Phosphorylation	PYFAAAYTPYHQKLA CCCEEECCHHHHHHH	16.79	24043423
25	Phosphorylation	FAAAYTPYHQKLAYY CEEECCHHHHHHHHH	14.75	24043423
44	Phosphorylation	EAQECNASPSSSGSG HHHHCCCCCCCCCCC	16.01	-
53	Phosphorylation	SSSGSGSSSFSSQTP CCCCCCCCCCCCCCC	38.64	-
56	Phosphorylation	GSGSSSFSSQTPASI CCCCCCCCCCCCCCC	24.39	-
59	Phosphorylation	SSSFSSQTPASIKEE CCCCCCCCCCCCCCC	23.83	-
69	Phosphorylation	SIKEEEGSPEKERPP CCCCCCCCCCCCCCC	32.92	30266825
97	Phosphorylation	YFQGDISSVVDEHFS EECCCHHHHHHHHHH	26.88	-
104	Phosphorylation	SVVDEHFSRALSQPS HHHHHHHHHHHHCCC	20.67	24275569
108	Phosphorylation	EHFSRALSQPSSYSP HHHHHHHHCCCCCCC	38.77	24275569
111	Phosphorylation	SRALSQPSSYSPSCT HHHHHCCCCCCCCCC	33.98	24275569
112	Phosphorylation	RALSQPSSYSPSCTS HHHHCCCCCCCCCCC	35.99	24275569
113	Phosphorylation	ALSQPSSYSPSCTSS HHHCCCCCCCCCCCC	29.01	24275569
114	Phosphorylation	LSQPSSYSPSCTSSK HHCCCCCCCCCCCCC	16.57	24275569
133	Phosphorylation	SGPWRDCSFPMSQRS CCCCCCCCCCCCCCC	36.35	-
248	Phosphorylation	PLLMPAASGRPARLA CCEEECCCCCCCEEE	37.12	-
264	Phosphorylation	APAPAPGSPPCELSG CCCCCCCCCCCCCCC	25.30	30266825
270	Phosphorylation	GSPPCELSGKGEPAG CCCCCCCCCCCCCCC	19.03	30266825

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VGLL2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VGLL2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VGLL2_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of VGLL2_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.