VCY1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VCY1_HUMAN
• UniProt AC: O14598
• Protein Name: Testis-specific basic protein Y 1
• Gene Name: VCY
• Organism: Homo sapiens (Human).
• Sequence Length: 125
• Protein Description: May mediate a process in spermatogenesis or may play a role in sex ratio distortion..
• Protein Sequence: MSPKPRASGPPAKAKETGKRKSSSQPSPSGPKKKTTKVAEKGEAVRGGRRGKKGAATKMAAVTAPEAESGPAAPGPSDQPSQELPQHELPPEEPVSEGTQHDPLSQESELEEPLSKGRPSTPLSP

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSPKPRASG ------CCCCCCCCC	41.45	30631047
8	Phosphorylation	MSPKPRASGPPAKAK CCCCCCCCCCCHHHH	53.78	28102081
22	Phosphorylation	KETGKRKSSSQPSPS HHHCCCCCCCCCCCC	38.97	25072903
23	Phosphorylation	ETGKRKSSSQPSPSG HHCCCCCCCCCCCCC	35.71	25072903
24	Phosphorylation	TGKRKSSSQPSPSGP HCCCCCCCCCCCCCC	53.88	25072903
27	Phosphorylation	RKSSSQPSPSGPKKK CCCCCCCCCCCCCCC	24.86	28102081
29	Phosphorylation	SSSQPSPSGPKKKTT CCCCCCCCCCCCCCC	72.56	28102081
34	Acetylation	SPSGPKKKTTKVAEK CCCCCCCCCCCHHHH	68.50	60611811
37	Acetylation	GPKKKTTKVAEKGEA CCCCCCCCHHHHCCH	44.68	60611813
120	Phosphorylation	PLSKGRPSTPLSP-- CHHCCCCCCCCCC--	41.10	23090842
121	Phosphorylation	LSKGRPSTPLSP--- HHCCCCCCCCCC---	30.82	22617229
124	Phosphorylation	GRPSTPLSP------ CCCCCCCCC------	29.75	20815410

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VCY1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VCY1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VCY1_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of VCY1_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.