VATD2_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VATD2_DROME
• UniProt AC: Q9NEF6
• Protein Name: Probable V-type proton ATPase subunit D 2
• Gene Name: Vha36-3
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 249
• Protein Description: Subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity)..
• Protein Sequence: MAAKDRLPIFPSRGAQTLMKSRLAGATKGHGLLKKKADALQMRFRLILGKIIETKTLMGQVMKEAAFSLAEVKFTTGDINQIVLQNVTKAQIKIRTKKDNVAGVTLPIFEPYTDGVDTYELAGLARGGQQLAKLKKNYQSAVRLLVQLASLQTSFVTLDDVIKVTNRRVNAIEHVIIPRINRTIEYIISELDELEREEFYRLKKIQDKKREARKASDKLRAEQRLLGQMAEAQEVQNILDEDGDEDLLF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
50	Acetylation	RFRLILGKIIETKTL HHHHHHHHHHHHHHH	36.75	21791702
105	Phosphorylation	KDNVAGVTLPIFEPY CCCCCCEEEEEECCC	26.37	22668510
118	Phosphorylation	PYTDGVDTYELAGLA CCCCCCCHHHHHHHH	19.25	22668510
119	Phosphorylation	YTDGVDTYELAGLAR CCCCCCHHHHHHHHH	12.41	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VATD2_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VATD2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VATD2_DROME !!

Protein-Protein Interaction

Oops, there are no PPI records of VATD2_DROME !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.