dbPTM

VATB_CAEEL - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VATB_CAEEL
UniProt AC	Q19626
Protein Name	Probable V-type proton ATPase subunit B
Gene Name	vha-12
Organism	Caenorhabditis elegans.
Sequence Length	491
Subcellular Localization
Protein Description	Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity). Required for necrotic cell death and epidermal cell fusion..
Protein Sequence	MAAVDVNQPITGHKSAIIRNYNTNPRLIYQTVCGVNGPLVILNDVKFPQFSEIVKITLPDGSKRSGQVLEISKNKAVVQVFEGTSGIDAKNTICEFTGDILRTPVSEDMLGRIFNGSGKPIDKGPPVLAEDFLDINGQPINPWSRIYPEEMIQTGISAIDVMNSIARGQKIPIFSASGLPHNEIAAQIVRQGGLVQLPDRPHEQTNFAIVFAAMGVNMETARFFKQDFEENGSMENVCLFLNLANDPTIERIITPRIALTSAEFLAYQCKKHVLVVLTDMSSYAEALREVSAAREEVPGRRGFPGYMYTDLATIYERAGRVEGRDGSITQIPILTMPNDDITHPIPDLTGYITEGQIYVDRQLHNRLIYPPINVLPSLSRLMKSAIGEGMTREDHSDVSNQLYACYAIGKDVQAMKAVVGEEALSSDDLLYLEFLTKFEKNFITQGHYENRSVFESLDIGWQLLRIFPREMLKRIPESTLEKYYPRGGAKE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
11	Phosphorylation	VDVNQPITGHKSAII CCCCCCCCCCCCEEE	39.66	28854356
84	Phosphorylation	VVQVFEGTSGIDAKN EEEEEECCCCCCCCC	19.31	30078680
85	Phosphorylation	VQVFEGTSGIDAKNT EEEEECCCCCCCCCC	44.61	30078680
175	Phosphorylation	GQKIPIFSASGLPHN CCCCCEEECCCCCHH	23.42	28854356
177	Phosphorylation	KIPIFSASGLPHNEI CCCEEECCCCCHHHH	39.40	28854356

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VATB_CAEEL !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VATB_CAEEL !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VATB_CAEEL !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of VATB_CAEEL !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VATB_CAEEL

Related Literatures of Post-Translational Modification