VATB3_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VATB3_ARATH
• UniProt AC: Q8W4E2
• Protein Name: V-type proton ATPase subunit B3
• Gene Name: VHA-B3
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 487
• Subcellular Localization: Vacuole membrane ; Peripheral membrane protein .
• Protein Description: Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells..
• Protein Sequence: MVETSIDMEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKFTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTENLIQEDHGEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDQFYSRDSTS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
21	Phosphorylation	EIGMEYRTVSGVAGP EECCEEEEECCCCCC	20.37	19880383
23	Phosphorylation	GMEYRTVSGVAGPLV CCEEEEECCCCCCEE	27.26	19880383
75	Phosphorylation	VQVFEGTSGIDNKFT EEEEECCCCCCCCCE	44.61	30291188
387	Sulfoxidation	KSAIGEGMTRKDHSD HHHHCCCCCCCCCHH	2.59	25693801
412	Sulfoxidation	IGKDVQAMKAVVGEE CCCCHHHHHHHHCCH	1.28	25693801
482	Phosphorylation	KTLDQFYSRDSTS-- HHHHHHHHCCCCC--	30.79	30407730
485	Phosphorylation	DQFYSRDSTS----- HHHHHCCCCC-----	29.46	29654922
486	Phosphorylation	QFYSRDSTS------ HHHHCCCCC------	42.62	19880383
487	Phosphorylation	FYSRDSTS------- HHHCCCCC-------	42.02	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VATB3_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VATB3_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VATB3_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of VATB3_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.