VATB1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VATB1_ARATH
• UniProt AC: P11574
• Protein Name: V-type proton ATPase subunit B1
• Gene Name: VHA-B1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 486
• Subcellular Localization: Vacuole membrane ; Peripheral membrane protein .
• Protein Description: Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells..
• Protein Sequence: MGTNDLDIEEGTLEIGMEYRTVSGVAGPLVILDKVKGPKYQEIVNIRLGDGSTRRGQVLEVDGEKAVVQVFEGTSGIDNKFTTVQFTGEVLKTPVSLDMLGRIFNGSGKPIDNGPPILPEAYLDISGSSINPSERTYPEEMIQTGISTIDVMNSIARGQKIPLFSAAGLPHNEIAAQICRQAGLVKRLEKTVDLLEDHGEDNFAIVFAAMGVNMETAQFFKRDFEENGSMERVTLFLNLANDPTIERIITPRIALTTAEYLAYECGKHVLVILTDMSSYADALREVSAAREEVPGRRGYPGYMYTDLATIYERAGRIEGRKGSITQIPILTMPNDDITHPTPDLTGYITEGQIYIDRQLHNRQIYPPINVLPSLSRLMKSAIGEGMTRKDHSDVSNQLYANYAIGKDVQAMKAVVGEEALSSEDLLYLEFLDKFERKFVMQGAYDTRNIFQSLDLAWTLLRIFPRELLHRIPAKTLDQFYSRDSTS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MGTNDLDIE ------CCCCCCCCC	32.97	-
3	Phosphorylation	-----MGTNDLDIEE -----CCCCCCCCCC	25.02	19880383
21	Phosphorylation	EIGMEYRTVSGVAGP EECCEEEEECCCCCC	20.37	19880383
23	Phosphorylation	GMEYRTVSGVAGPLV CCEEEEECCCCCCEE	27.26	19880383
75	Phosphorylation	VQVFEGTSGIDNKFT EEEEECCCCCCCCCE	44.61	30291188
481	Phosphorylation	KTLDQFYSRDSTS-- HHHHHHHHCCCCC--	30.79	30407730
484	Phosphorylation	DQFYSRDSTS----- HHHHHCCCCC-----	29.46	29654922
485	Phosphorylation	QFYSRDSTS------ HHHHCCCCC------	42.62	19880383
486	Phosphorylation	FYSRDSTS------- HHHCCCCC-------	42.02	19880383

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VATB1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VATB1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VATB1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SCL3_ARATH	SCL3	physical	17081979
CIPKO_ARATH	SOS2	physical	17875927

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.