VAMP3_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VAMP3_RAT
• UniProt AC: P63025
• Protein Name: Vesicle-associated membrane protein 3
• Gene Name: Vamp3
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 103
• Subcellular Localization: Membrane ; Single-pass type IV membrane protein . Cell junction, synapse, synaptosome.
• Protein Description: SNARE involved in vesicular transport from the late endosomes to the trans-Golgi network..
• Protein Sequence: MSTGVPSGSSAATGSNRRLQQTQNQVDEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASQFETSAAKLKRKYWWKNCKMWAIGISVLVIIVIIIIVWCVS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSTGVPSGS ------CCCCCCCCC	33.59	-
2	Phosphorylation	------MSTGVPSGS ------CCCCCCCCC	33.59	23984901
3	Phosphorylation	-----MSTGVPSGSS -----CCCCCCCCCC	40.68	23984901
7	Phosphorylation	-MSTGVPSGSSAATG -CCCCCCCCCCCCCC	49.23	23984901
9	Phosphorylation	STGVPSGSSAATGSN CCCCCCCCCCCCCCH	22.57	23984901
10	Phosphorylation	TGVPSGSSAATGSNR CCCCCCCCCCCCCHH	26.00	23984901
13	Phosphorylation	PSGSSAATGSNRRLQ CCCCCCCCCCHHHHH	40.64	27097102
15	Phosphorylation	GSSAATGSNRRLQQT CCCCCCCCHHHHHHH	23.86	27097102
39	Acetylation	IMRVNVDKVLERDQK HHCCCHHHHHHHHHH	44.42	22902405
39	Ubiquitination	IMRVNVDKVLERDQK HHCCCHHHHHHHHHH	44.42	-
46	Acetylation	KVLERDQKLSELDDR HHHHHHHHHHHHHHH	59.26	22902405
46	Ubiquitination	KVLERDQKLSELDDR HHHHHHHHHHHHHHH	59.26	-
48	Phosphorylation	LERDQKLSELDDRAD HHHHHHHHHHHHHHH	43.05	25403869
62	Phosphorylation	DALQAGASQFETSAA HHHHHHHHHHHHHHH	34.19	30240740
66	Phosphorylation	AGASQFETSAAKLKR HHHHHHHHHHHHHHH	25.59	27097102
67	Phosphorylation	GASQFETSAAKLKRK HHHHHHHHHHHHHHH	21.02	27097102
70	Ubiquitination	QFETSAAKLKRKYWW HHHHHHHHHHHHHHH	55.01	-
72	Ubiquitination	ETSAAKLKRKYWWKN HHHHHHHHHHHHHHH	46.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VAMP3_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VAMP3_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VAMP3_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of VAMP3_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.