VAMP1_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VAMP1_RAT
• UniProt AC: Q63666
• Protein Name: Vesicle-associated membrane protein 1
• Gene Name: Vamp1
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 118
• Subcellular Localization: Isoform 1: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type IV membrane protein. Cell junction, synapse, synaptosome.; Isoform 2: Cytoplasmic vesicle membrane; Single-pass type IV membrane protein. Isoforms 2 and 3
• Protein Description: Involved in the targeting and/or fusion of transport vesicles to their target membrane..
• Protein Sequence: MSAPAQPPAEGTEGAAPGGGPPGPPPNTTSNRRLQQTQAQVEEVVDIMRVNVDKVLERDQKLSELDDRADALQAGASVFESSAAKLKRKYWWKNCKMMIMLGAICAIIVVVIVIYIFT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Acetylation	IMRVNVDKVLERDQK HHCCCHHHHHHHHHH	44.42	56265399
61	Ubiquitination	KVLERDQKLSELDDR HHHHHHHHHHHHHHH	59.26	-
63	Phosphorylation	LERDQKLSELDDRAD HHHHHHHHHHHHHHH	43.05	25403869

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VAMP1_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VAMP1_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VAMP1_RAT !!

Protein-Protein Interaction

Oops, there are no PPI records of VAMP1_RAT !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.