dbPTM

UTP6_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UTP6_MOUSE
UniProt AC	Q8VCY6
Protein Name	U3 small nucleolar RNA-associated protein 6 homolog
Gene Name	Utp6
Organism	Mus musculus (Mouse).
Sequence Length	597
Subcellular Localization	Nucleus, nucleolus.
Protein Description	Involved in nucleolar processing of pre-18S ribosomal RNA..
Protein Sequence	MAEIIQERIEDRIPELEQLERIGLFSHAEIKAIIKKASDLEYKIHRRTLLKEDFINYVQYEINLLELIQRRRARIKYSFKKDEIEYSMVHRVQGVFGRASAKWKDDVQLWLSYIVFCKKWGTKTHLSKIFSAMLAIHSNKPALWIMAAKWEMEDRLSSESARQLFLRALRFHPECPKLYQEYFRMELMHAEKLRKEKQEFEKAAMDMGDFDHPEEILKGELARIIYKNSISKIKGAEFHVSLLAIAQLFDFAKDLQKEIYDDLQALHTDDPLTWDYVARRELEIESQPGEEQPVSKQAKAVEMGRREERCCAVYEEAVKALPTEAMWKCYITFCLERFSKKTSSVPLRGQRLERTMLAFRKAHELKLLSEVQYKQWIDLLLRQDLFKEALQVAEAGTELFKDSVTMWQTKLQVLIDSKSPDVEMRFEEAFAHLKPQVCLPLWISWAEWSESAKSQEDTEAIFKKAIIAVTGASSVTLKEKYLDWAYRSGGYKKARAVFKSLQESRPFSVEFFRKMMQFEKEQEPCKMVNLREYYERALREFGTSDSDLWMDYIKEELNHPFGKPENCGQIYWRAMKMLQGQSAELFVAKHAMHQAGH

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	KAIIKKASDLEYKIH HHHHHHHHHCHHHHH	52.16	25619855
122	Phosphorylation	VFCKKWGTKTHLSKI HHHHHHCCHHHHHHH	31.49	-
158	Phosphorylation	EMEDRLSSESARQLF HHHHHCCHHHHHHHH	39.91	21454597
160	Phosphorylation	EDRLSSESARQLFLR HHHCCHHHHHHHHHH	30.60	21454597
286	Phosphorylation	RRELEIESQPGEEQP HHHEEECCCCCCCCC	47.54	27566939
488	Phosphorylation	YLDWAYRSGGYKKAR HHHHHHHCCCHHHHH	24.72	-
491	Phosphorylation	WAYRSGGYKKARAVF HHHHCCCHHHHHHHH	16.91	-
495	Dimethylation	SGGYKKARAVFKSLQ CCCHHHHHHHHHHHH	39.91	-
500	O-linked_Glycosylation	KARAVFKSLQESRPF HHHHHHHHHHHCCCC	24.66	30059200
505	Dimethylation	FKSLQESRPFSVEFF HHHHHHCCCCCHHHH	35.21	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UTP6_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UTP6_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UTP6_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of UTP6_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UTP6_MOUSE

Related Literatures of Post-Translational Modification