dbPTM

UTP10_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UTP10_SCHPO
UniProt AC	O60179
Protein Name	U3 small nucleolar RNA-associated protein 10
Gene Name	utp10
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	1649
Subcellular Localization	Nucleus, nucleolus.
Protein Description	Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I together with a subset of U3 proteins required for transcription (t-UTPs). Involved in ribosome biosynthesis (By similarity)..
Protein Sequence	MASSLQKQLKNIQSNNVLKINKIRRAPSLLYDPKVAADMDLEEIYVTAVSGFHELAVHEPRLLYFEKTLLGEQSVQVDRVLLNRTENEKIDLECVQILRLLAPFFTEKNALKVLEWLIRRFSIHEYVSDEFILSFLPFHDHPFFARILGCSKPKSRPLLFLENAIKMPVTLSRADIVHALSRDKEFFAMFAQFVQNTAESHNMYPELARFWAGTMMEVLVAWHSSNEDPNVLLDRFFLRVSYAVSYVSSIDFQIAGFMLLSSIAASLPLSPSIIPPLVSAITDRLSFDNIKPALICVGHLLQFCSSFEFDHEQLEKLESFGASSLLIELSQEHRLDEFFVSYWVSLIKSRKQKDKKRLISLLDTSISQIRVTHEQAKFLLSVIPVNQDFKALQSYRRILDSVIQPERKEGKLDNLINTLQDKKKSSTFSKKDREVLLKKISEIDSQTSFEQCLAYADSAADLDSSVFISLLSKFGDKIPFLLFCIANGSERIIILSLIELRKTIEENKDVDYQIILPVVLYSLQSKDTEVRSRALNLILTFLELRNENLEFSIIYGMDDNDNKNLRWLSPVETKYYCSDLLLDRSSEIGLDGTYLFSYIPERLFTEKKPKNASKEIAVTSFLSSHAACSKLSNVRVLLLEILTRVHGKVEDAKMQILLPRLEQLSEFNSEKFKTVSKREVEALVNCFNHTSFTSLLSFLSSNIVLSQAICRRIVEIQSHLKDPQRLEFVKAVISQDEQPHYYVDVLDSIKIPDTVFKKLIGSVRLVKEKNPAIAKRKRIDSHIFDGDVQRLTRILELLETKNAASYPKLASPLFEVLNSVIALKEDIVSSNYLLQLLLGLLYEMIGASPITELSPSIRIDTLVGCIRSTNNPQIQNKALLLVSALANAAPEAVLHGVMPIFTFMGSTVLSRDDAFSIHVIEQTVKTVISALIRLGKDFDSSLLVSCFVNAFPHIPQHRRLRLYRLVLQTIGSNRFLSVVLIQFAEKMLLAKSTNVVAIHDFCLTLVQSFSVADRIGSINQCSRFCLKSLEEQSNSDSNGKAVSLIKLDELPMDVDLATLGSLRVKVLELISLVSKAKNFAFDLAKIMENSVDSFVEIQAGLFESIKLLITLSQQSSNEMELGHVYVALRSVIHLLPNELFCTVLGKLLHDERALLRRKALSIVQQRVQQGSKVSALTALIPDVTYNISNYSDEETTQLAMDCLAVMAKRFSASPELFISPIEVVSGPYGLKNSARDVQVSAIVCITVLTNTLAARILPYLADIVNYSLSILDDARKDPEGDLLELACFSMMIDFFKVLPEFSSSYVEPTIKCALASDRAFEHDAIGELLFETIANFIPTRLLMKSIFAAWPECARLGSTAALRLLELIELALQNSSRSAIGTVYKSIFKFFLDSFDSRRSLLFAEDVDNVETQAVNVFLKFVMKLSDTTFRPLFLHLHSWALEDLYETDPSGIVSRQTFFYNFLTIFLDTLKSIVTNYYAYVLDDTIELLSSKDTNSEVRHLVNSSLVSAFENDTEEFWMVPARFGKISPVLIEQIQYAPLLDDKVLVKAIVELASVASSSDNFRSMNTQLLQYLRSSNINARLLAIQIQTQLYGRLGENWISTLPQSVPFIAELMEDDDDQVETATAELVRIIDDRLGENESLQDYLT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
155	Phosphorylation	LGCSKPKSRPLLFLE HCCCCCCCCCEEEHH	47.89	25720772
1643	Phosphorylation	DRLGENESLQDYLT- HCCCCCCCHHHHCC-	42.80	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UTP10_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UTP10_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UTP10_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of UTP10_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UTP10_SCHPO

Related Literatures of Post-Translational Modification