UTF1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UTF1_HUMAN
• UniProt AC: Q5T230
• Protein Name: Undifferentiated embryonic cell transcription factor 1
• Gene Name: UTF1 {ECO:0000312|HGNC:HGNC:12634}
• Organism: Homo sapiens (Human).
• Sequence Length: 341
• Subcellular Localization: Nucleus .
• Protein Description: Acts as a transcriptional coactivator of ATF2..
• Protein Sequence: MLLRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSAALAQQQVRRTPAQCRRRYKFLKDKFREAHGQPPGPFDEQIRKLMGLLGDNGRKRPRRRSPGSGRPQRARRPVPNAHAPAPSEPDATPLPTARDRDADPTWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDPDSPPGRPEDCAPPPAAPPSLNTALLQTLGHLGDIANILGPLRDQLLTLNQHVEQLRGAFDQTVSLAVGFILGSAAAERGVLRDPCQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
18	Phosphorylation	LAPPAPPSPASPDPE CCCCCCCCCCCCCCC	31.85	19664995
21	Phosphorylation	PAPPSPASPDPEPRT CCCCCCCCCCCCCCC	32.97	26503892
28	Phosphorylation	SPDPEPRTPGDAPGT CCCCCCCCCCCCCCC	42.19	21406692
35	Phosphorylation	TPGDAPGTPPRRPAS CCCCCCCCCCCCCCC	29.12	19664994
42	Phosphorylation	TPPRRPASPSALGEL CCCCCCCCHHHHHHC	23.28	19664994
44	Phosphorylation	PRRPASPSALGELGL CCCCCCHHHHHHCCC	33.36	21406692
54	Phosphorylation	GELGLPVSPGSAQRT HHCCCCCCCCCCCCC	22.92	19664994
57	Phosphorylation	GLPVSPGSAQRTPWS CCCCCCCCCCCCCCC	25.31	21406692
99	Phosphorylation	LPTYRRVSAALAQQQ CHHHHHHHHHHHHHH	13.15	30242111
118	Phosphorylation	PAQCRRRYKFLKDKF HHHHHHHHHHHHHHH	12.32	-
159	Phosphorylation	RKRPRRRSPGSGRPQ CCCCCCCCCCCCCCC	31.62	21406692
162	Phosphorylation	PRRRSPGSGRPQRAR CCCCCCCCCCCCCCC	34.71	21406692
181	Phosphorylation	NAHAPAPSEPDATPL CCCCCCCCCCCCCCC	64.96	27422710
186	Phosphorylation	APSEPDATPLPTARD CCCCCCCCCCCCCCC	32.51	25367160
199	Phosphorylation	RDRDADPTWTLRFSP CCCCCCCCEEEEECC	31.46	21406692
201	Phosphorylation	RDADPTWTLRFSPSP CCCCCCEEEEECCCC	15.55	21406692
205	Phosphorylation	PTWTLRFSPSPPKSA CCEEEEECCCCCCCC	20.31	27422710
207	Phosphorylation	WTLRFSPSPPKSADA EEEEECCCCCCCCCC	53.27	21406692
211	Phosphorylation	FSPSPPKSADASPAP ECCCCCCCCCCCCCC	36.84	29888752
215	Phosphorylation	PPKSADASPAPGSPP CCCCCCCCCCCCCCC	23.34	29888752
220	Phosphorylation	DASPAPGSPPAPAPT CCCCCCCCCCCCCCC	27.01	29888752
245	Phosphorylation	APVRGPGSPPPPPAR CCCCCCCCCCCCCCC	37.05	19664995

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UTF1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UTF1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UTF1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATF2_HUMAN	ATF2	physical	9524124

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.