UT14A_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UT14A_MOUSE
• UniProt AC: Q640M1
• Protein Name: U3 small nucleolar RNA-associated protein 14 homolog A
• Gene Name: Utp14a
• Organism: Mus musculus (Mouse).
• Sequence Length: 767
• Subcellular Localization: Nucleus, nucleolus.
• Protein Description: May be required for ribosome biogenesis..
• Protein Sequence: MNSIKATKGLLALSQQDDLMDLTSNYPLSASEDEGDSDGERKHQKLLEAIGSLSGKNRWKLPERSEAGLKVSEFNVSSEGSGEKLALSDLLGPLKPSSSLAAVKKQLSRVKSKKTLELPLHKREVEQIHREVAFSKTSQTLSKWDSVVQKNREAEQLVFPLEKEPSSFAPMEHVFREWKARTPLEQEVFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKIRRAELQRARALQSYYEARARRMKKIKSKKYHKIVKKGKAKKALKDFEQLRKVDPDAALEELEKMEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLAKNKELTQKLQVVSESEEEGGADEEEALVPDIVNEVQKTADGPNPWMLRSCSRDAKENEIQADSEQLPESAAHEFPENEENDKPVAEEDELLKELEKRRSLRKRSELNQAAEPLGNQETKDSTSQEVLSELRALSKKLSKENHLSKKQKKSPAKAVDLVWEEEPAPEEDEPLLLQRPERMRTLEELEELGKEDSLPNKERPRPSVEGEQVRRNPQNHSKGKNKKEQMISLQNLLTTRTPSVTSLALPTTVEELEDEGARDQKQMIKEAFAGDDVIKEFLKEKREAIQANKPKAVDLTLPGWGEWGGMNLKPSARKRRRFLIKAPEGPPRKDKNLPNVIISEKRNIHAAAHQVRVLPYPFTHHQQFERTIQNPIGSTWNTQRAFQKLTAPKVVTKPGHIIKPITAEDVDCRSSPRSDVPVMQSNPKQHSKHQKQRKKSSIG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	QDDLMDLTSNYPLSA CCCHHHHHCCCCCCC	15.63	22324799
24	Phosphorylation	DDLMDLTSNYPLSAS CCHHHHHCCCCCCCC	41.48	22324799
26	Phosphorylation	LMDLTSNYPLSASED HHHHHCCCCCCCCCC	12.81	25159016
29	Phosphorylation	LTSNYPLSASEDEGD HHCCCCCCCCCCCCC	25.83	22324799
31	Phosphorylation	SNYPLSASEDEGDSD CCCCCCCCCCCCCCC	42.05	22324799
37	Phosphorylation	ASEDEGDSDGERKHQ CCCCCCCCCHHHHHH	59.37	22942356
52	Phosphorylation	KLLEAIGSLSGKNRW HHHHHHHHCCCCCCC	17.16	26745281
54	Phosphorylation	LEAIGSLSGKNRWKL HHHHHHCCCCCCCCC	49.79	26745281
77	Phosphorylation	KVSEFNVSSEGSGEK EEEEEECCCCCCCCE	24.63	28066266
78	Phosphorylation	VSEFNVSSEGSGEKL EEEEECCCCCCCCEE	41.51	28066266
81	Phosphorylation	FNVSSEGSGEKLALS EECCCCCCCCEEHHH	39.46	28066266
182	Phosphorylation	FREWKARTPLEQEVF HHHHHCCCHHHHHHH	36.77	26745281
200	Phosphorylation	HKNKQPVTDPLLTPV HCCCCCCCCCCCCHH	38.28	-
205	Phosphorylation	PVTDPLLTPVEKASL CCCCCCCCHHHHHHH	32.73	25159016
258	Acetylation	KYHKIVKKGKAKKAL HHHHHHHHCHHHHHH	55.54	7718999
296	Phosphorylation	ARMMERMSLKHQNSG HHHHHHHCHHHCCCC	40.25	-
302	Phosphorylation	MSLKHQNSGKWAKSK HCHHHCCCCHHHHHH	34.87	-
308	Phosphorylation	NSGKWAKSKAIMAKY CCCHHHHHHHHHHHH	21.41	-
314	Acetylation	KSKAIMAKYDLEARQ HHHHHHHHHCHHHHH	23.16	22826441
341	Phosphorylation	TQKLQVVSESEEEGG HHHHHCCCCCHHCCC	36.23	27087446
343	Phosphorylation	KLQVVSESEEEGGAD HHHCCCCCHHCCCCC	42.68	27087446
379	Phosphorylation	PWMLRSCSRDAKENE CCHHHHCCHHHHHCC	34.15	-
391	Phosphorylation	ENEIQADSEQLPESA HCCCCCCHHHCCHHH	30.20	25338131
431	Citrullination	KRRSLRKRSELNQAA HHHHHHHHHHHHHHH	29.00	24463520
431	Citrullination	KRRSLRKRSELNQAA HHHHHHHHHHHHHHH	29.00	-
432	Phosphorylation	RRSLRKRSELNQAAE HHHHHHHHHHHHHHC	49.85	29514104
449	Phosphorylation	GNQETKDSTSQEVLS CCCCCCCCCHHHHHH	31.36	30635358
450	Phosphorylation	NQETKDSTSQEVLSE CCCCCCCCHHHHHHH	44.56	30635358
451	Phosphorylation	QETKDSTSQEVLSEL CCCCCCCHHHHHHHH	28.44	30635358
456	Phosphorylation	STSQEVLSELRALSK CCHHHHHHHHHHHHH	39.50	21659604
466	Phosphorylation	RALSKKLSKENHLSK HHHHHHHHHHHCCCH	46.97	28418008
467	Acetylation	ALSKKLSKENHLSKK HHHHHHHHHHCCCHH	73.33	8277217
473	Acetylation	SKENHLSKKQKKSPA HHHHCCCHHHCCCHH	66.63	8277227
531	Phosphorylation	NKERPRPSVEGEQVR CCCCCCCCCCHHHHH	33.80	25159016
556	Phosphorylation	NKKEQMISLQNLLTT CHHHHHHHHHHHHCC	20.68	25338131
562	Phosphorylation	ISLQNLLTTRTPSVT HHHHHHHCCCCCCCC	19.87	28059163
563	Phosphorylation	SLQNLLTTRTPSVTS HHHHHHCCCCCCCCE	32.30	25338131
565	Phosphorylation	QNLLTTRTPSVTSLA HHHHCCCCCCCCEEE	20.16	25159016
567	Phosphorylation	LLTTRTPSVTSLALP HHCCCCCCCCEEECC	37.10	26824392
569	Phosphorylation	TTRTPSVTSLALPTT CCCCCCCCEEECCCC	23.51	25159016
570	Phosphorylation	TRTPSVTSLALPTTV CCCCCCCEEECCCCH	14.97	25159016
575	Phosphorylation	VTSLALPTTVEELED CCEEECCCCHHHHHH	44.30	25777480
576	Phosphorylation	TSLALPTTVEELEDE CEEECCCCHHHHHHC	24.79	25777480
586	Citrullination	ELEDEGARDQKQMIK HHHHCCCHHHHHHHH	58.72	24463520
586	Citrullination	ELEDEGARDQKQMIK HHHHCCCHHHHHHHH	58.72	-
730	Phosphorylation	GHIIKPITAEDVDCR CCEECCEEHHHCCCC	32.30	25367039
738	Phosphorylation	AEDVDCRSSPRSDVP HHHCCCCCCCCCCCC	51.53	26824392
739	Phosphorylation	EDVDCRSSPRSDVPV HHCCCCCCCCCCCCC	12.65	26824392
742	Phosphorylation	DCRSSPRSDVPVMQS CCCCCCCCCCCCCCC	46.47	26643407
749	Phosphorylation	SDVPVMQSNPKQHSK CCCCCCCCCHHHCCH	36.68	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UT14A_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UT14A_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UT14A_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of UT14A_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.