USMG5_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: USMG5_MOUSE
• UniProt AC: Q78IK2
• Protein Name: Up-regulated during skeletal muscle growth protein 5
• Gene Name: Usmg5
• Organism: Mus musculus (Mouse).
• Sequence Length: 58
• Subcellular Localization: Mitochondrion membrane; Single-pass membrane protein.
• Protein Description: Plays a critical role in maintaining the ATP synthase population in mitochondria..
• Protein Sequence: MAGAESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRPKKTPAVKAT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
17	Succinylation	FQFTGIKKYFNSYTL EEECCHHHHCCEEEC	53.83	24315375

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of USMG5_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of USMG5_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of USMG5_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of USMG5_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Acetylation

"Substrate and functional diversity of lysine acetylation revealed bya proteomics survey.";
Kim S.C., Sprung R., Chen Y., Xu Y., Ball H., Pei J., Cheng T.,Kho Y., Xiao H., Xiao L., Grishin N.V., White M., Yang X.-J., Zhao Y.;
Mol. Cell 23:607-618(2006).
Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-16 AND LYS-17, AND MASSSPECTROMETRY.
PubMed: 16916647