US107_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: US107_SCHPO
• UniProt AC: Q8WZK0
• Protein Name: U1 snRNP-associated protein usp107
• Gene Name: usp107
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 695
• Subcellular Localization: Cytoplasm. Nucleus.
• Protein Description: Component of the U1 snRNP particle, which recognizes and binds the 5'-splice site of pre-mRNA. Together with other non-snRNP factors, U1 snRNP forms the spliceosomal commitment complex, that targets pre-mRNA to the splicing pathway..
• Protein Sequence: MQRQNTQAAGMPMMPQVPMVGNGVPYVVPIQPVFAPLPPDYRSLYKKLYGQGAFLVDNPVEASSPYDFSQPILKFGKLPIKQVLRDNESQQKDRKNLPRNQKSNEIQEKQTFQTPSSEKSTTERESRPFVPPNSQQMRRMLFIGNIPKELDDFWMDKILRLSGKLASWRRVADADNSMTSFGFAEFESNEQFSRALEALNDFVVPPLYEGGPSTRLSLITDVENEGLYREWQTSRYARNKQKEINILQQIRFNLERICQDIGNFDVRSRIERAARQAREKNEKLLQNVKTSEIPINAADLEGINPELLPVIEEEIRSFRDQSAMKKREKQRSKDEYASLYKEYTRKEQEKLRKQNDDLQNLLSKHRISRIPMSTVNAFLRAEDSIPESFSDEQAYYEEKRRKDQLEAEEYYARERRWMNREKARTAALEREAAREEEERVNNTSFGTYLSEKLASFDDDEEARVSRDEYFVDRAAWIRHRAVARAREEDADALDRKEEERELRTRGEGATVETENYVENGKLVTSEMPQHENGPFKIKIQTKKPAVPSERREFGLPERLLLEEEDEEPQGYSPNPQKPKPAMEENDAEKTKRLRSLIEKIPVEAESLWALPIDWSKVTEDLLKEEMQAFVTKKIIEYIGIQEDSLITFTIDHIRQHKGAEQLVSELDLALAEDAPEFVSKVYRYLHVLLILRSEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
444	Phosphorylation	EERVNNTSFGTYLSE HHHHHCCCHHHHHHH		28889911
571	Phosphorylation	EDEEPQGYSPNPQKP CCCCCCCCCCCCCCC		29996109
572	Phosphorylation	DEEPQGYSPNPQKPK CCCCCCCCCCCCCCC		29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of US107_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of US107_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of US107_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RU1A_SCHPO	usp102	physical	22064476
SNF5_SCHPO	snf5	genetic	22681890
ARP42_SCHPO	arp42	genetic	22681890
SOL1_SCHPO	sol1	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.