| UniProt ID | URGCP_MOUSE | |
|---|---|---|
| UniProt AC | Q5NCI0 | |
| Protein Name | Up-regulator of cell proliferation | |
| Gene Name | Urgcp | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 926 | |
| Subcellular Localization | Cytoplasm . Nucleus . In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei.. | |
| Protein Description | May be involved in cell cycle progression through the regulation of cyclin D1 expression.. | |
| Protein Sequence | MASPGIEVELLVKGHSDLGEVAPEVKPSDSQTSVAIADLEWREMEGDDCGFHYGDGTNEAQDNDFPTVERSRLQEMLSLLGLETYQAQKLTLQDSLQISFDSMKNWAPQVPKDLPWHFLRKLQALNAEARNTTMVLDVPPEAWPAEKESQAEEEMMYWDPAEDVAADIYSFSELPMPDTPVNPLDLLCALLLSSDTFLQQEVLLKMSLCQFALPLVLPDSENHYHTFLLWALRGVVRTWWFQPLRSLGSFREDSVVLSRVPTFAFVRMDVSSNSKSQLLNAVLSPARRQWDCFWHRDLNLGTNPREISDGLVEISWFFPSGKEDLDVFPEPMAFLNLRGDIGSHWLQFKLLTEVSSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNRLIPVLKIDHSHVLVKVSSTDSEGFVRRIRAIMCSVARSPCRRVSVEDMAHAARKLGLRVDEDFEECQKAKDRMEKILRKIKDVDAYKRDELRLQGEPARRAAQAEREFCQLQWVPEPPEKHRAELRRRVLELRVQQNGQEPTSGVQEFILGISSPSPSERQYFLRWMEWGLARLGQPRPRQPPETLLTLRPKLGGPSDLTEPLWPEPLGVEHFLREMGQFYEAESCLIEAGRLPAGQRRFAHFPGVAVELLLGGLPLELVDGATLSIPVRWVTGLLKELHTRLDRRSRLVVLSALGVPGTGKSTLLNTMFGLKFATGRSCSPRGAFMQLLPVAEGFSQDLGCDQILVIDSGGLISGALASAGDRFELEASLATLLMGLSNVTVVSLAETKDIPPAVLHAFLRLEKMGHMPNYQFVYQNLHDLPVPSPKPRDRRQLLDPPSDLSRATHLEKQGGGFRTLAGLAERQHVWHIPALWHGAPPMAAVSLGYSEAIFELKRCLLENIRNGLSNQNQNIQQLIELLRRL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MASPGIEVEL -----CCCCCEEEEE | 23.51 | 30352176 | |
| 237 | Dimethylation | WALRGVVRTWWFQPL HHHHHHHHHHCCHHH | 23.40 | - | |
| 237 | Methylation | WALRGVVRTWWFQPL HHHHHHHHHHCCHHH | 23.40 | 18965979 | |
| 254 | Phosphorylation | LGSFREDSVVLSRVP CCCCCCCEEEEECCC | 14.90 | 24899341 | |
| 276 | Phosphorylation | DVSSNSKSQLLNAVL ECCCCCHHHHHHHHH | 26.36 | - | |
| 379 | Phosphorylation | LLYSMKESTTKYYFI HHHCCCCCCCEEEEE | 35.54 | - | |
| 447 | Phosphorylation | RSPCRRVSVEDMAHA CCCCCCCCHHHHHHH | 20.27 | 28507225 | |
| 829 | Phosphorylation | LHDLPVPSPKPRDRR HHCCCCCCCCCCCHH | 45.87 | 24719451 | |
| 835 | Methylation | PSPKPRDRRQLLDPP CCCCCCCHHHHCCCC | 29.53 | 16188935 | |
| 906 | Methylation | RCLLENIRNGLSNQN HHHHHHHHHCCCCCC | 42.62 | 16186183 | |
| 924 | Methylation | QQLIELLRRL----- HHHHHHHHHC----- | 50.94 | 16186191 | |
| 925 | Methylation | QLIELLRRL------ HHHHHHHHC------ | 44.72 | 16186199 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of URGCP_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of URGCP_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of URGCP_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of URGCP_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
