dbPTM

UMPS_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UMPS_MOUSE
UniProt AC	P13439
Protein Name	Uridine 5'-monophosphate synthase
Gene Name	Umps
Organism	Mus musculus (Mouse).
Sequence Length	481
Subcellular Localization
Protein Description
Protein Sequence	MEVASQALGPLVTELYDVQAFKFGSFVLKSGLSSPVYIDLRGIVSRPRLLSQVADILFQTAKNAGISFDSVCGVPYTALPLATVICSANHIPMLIRRKETKDYGTKRLVEGEINPGQTCLVIEDVVTSGASVLETVEVLQKEGLKVTDAIVLLDREQGGKDKLQAQGIRLHAVCTLSQMLEILQQQEKIDADMVGRVKRFIQENVFSAANHNGLPPPEKKACKELSFGARAELPGTHPLASKLLRLMQKKETNLCLSADVSEARELLQLADALGPSICMLKTHVDILNDFTLDVMEELTALAKRHEFLIFEDRKFADIGNTVKKQYESGTFKIASWADIVNAHVVPGSGVVKGLQEVGLPLHRACLLIAEMSSAGSLATGNYTKAAVGMAEEHCEFVIGFISGSRVSMKPEFLHLTPGVQLETGGDHLGQQYNSPQEVIGKRGSDVIIVGRGILAAANRLEAAEMYRKAAWEAYLSRLAVQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
37	Phosphorylation	SGLSSPVYIDLRGIV CCCCCCEEEECCHHH	7.66	22817900
51	Phosphorylation	VSRPRLLSQVADILF HCCHHHHHHHHHHHH	27.48	26745281
162	Acetylation	REQGGKDKLQAQGIR HHHCCHHHHHHCHHH	46.08	22826441
162	Malonylation	REQGGKDKLQAQGIR HHHCCHHHHHHCHHH	46.08	26320211
174	S-nitrosocysteine	GIRLHAVCTLSQMLE HHHHHHHHHHHHHHH	3.08	-
223	Ubiquitination	PPEKKACKELSFGAR CCCHHHHHHCCCCCC	67.56	22790023
278	S-palmitoylation	DALGPSICMLKTHVD HHHCHHEEEEEHHHH	2.83	28526873
324	Malonylation	DIGNTVKKQYESGTF CCCHHHHHHHHCCCE	54.50	26320211

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UMPS_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UMPS_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UMPS_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of UMPS_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UMPS_MOUSE

Related Literatures of Post-Translational Modification