ULBP3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ULBP3_HUMAN
• UniProt AC: Q9BZM4
• Protein Name: UL16-binding protein 3
• Gene Name: ULBP3
• Organism: Homo sapiens (Human).
• Sequence Length: 244
• Subcellular Localization: Cell membrane ; Lipid-anchor, GPI-anchor .
• Protein Description: Binds and activates the KLRK1/NKG2D receptor, mediating natural killer cell cytotoxicity..
• Protein Sequence: MAAAASPAILPRLAILPYLLFDWSGTGRADAHSLWYNFTIIHLPRHGQQWCEVQSQVDQKNFLSYDCGSDKVLSMGHLEEQLYATDAWGKQLEMLREVGQRLRLELADTELEDFTPSGPLTLQVRMSCECEADGYIRGSWQFSFDGRKFLLFDSNNRKWTVVHAGARRMKEKWEKDSGLTTFFKMVSMRDCKSWLRDFLMHRKKRLEPTAPPTMAPGLAQPKAIATTLSPWSFLIILCFILPGI

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MAAAASPAILPRL --CCCCCCCCHHHHH		23186163
37	N-linked_Glycosylation	DAHSLWYNFTIIHLP CHHHHEEEEEEEECC		UniProtKB CARBOHYD
55	Phosphorylation	QQWCEVQSQVDQKNF CCCEEEHHCCCCCCE		29978859
209	O-linked_Glycosylation	RKKRLEPTAPPTMAP HHHCCCCCCCCCCCC		55826737
213	O-linked_Glycosylation	LEPTAPPTMAPGLAQ CCCCCCCCCCCCCCC		55826741
217	GPI-anchor	APPTMAPGLAQPKAI CCCCCCCCCCCCCHH		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ULBP3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ULBP3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ULBP3_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of ULBP3_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.