dbPTM

UFSP2_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UFSP2_DROME
UniProt AC	Q9VUR0
Protein Name	Probable Ufm1-specific protease 2
Gene Name	UFSP2
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	607
Subcellular Localization
Protein Description	Thiol protease which recognizes and hydrolyzes the peptide bond at the C-terminal Gly of UFM1, a ubiquitin-like modifier protein bound to a number of target proteins. Does not hydrolyze SUMO1 or ISG15 ubiquitin-like proteins..
Protein Sequence	MLPKLKISAFLLKRLERTKQQCSGCLFGVFYGEGTLLLLSFNIESSLGQLNYEQIQHRFPAELDLCGLVKFGGCTDGEAHLNEVIKSVDITDNPILLQCELGTLVGLRASFFVHGKLEEVPYEVMEAHQLYNDFCFTRLQCGFFLQTAATPESVAREMHVLRKRVADGNLVFNVPQTKIFINNYGPLDKQFSGDSQIQDLIDVIPTPGHEKETASVDKKKLKGQNTPVKRLAPTGCDYEVIPIDVMRSRSRDPVSGEPPHPALSIAVTNEEQIRVQVPLEIEAMAILCRKTKLQRLYDVLIESICRGLRLFELSLIEHLTESGSGKLLVPASYHFYPQEFGHFVSCAYLEGLSDDTPSMLMRRKRLHRQFALPISRPYFRRANQMLFLGETEDAPWTPLLNTHIGLRPSGVVDGKEYLVNGNYHYYHYLQQQVQDKGWGCAYRSLQTICSWFVLQGYTNAPIPTHLEVQEYLHKINDKPAAFVGSSQWIGSTEISMCLQGFLNVDSKILHVASGAELATIASELAMHFQTQGTPVMIGGGVLAHTIIGVDYCVQTGQVKFLILDPHYTGADDLATIQIKGWCGWKGMDFWAKGSYYNLCMPQRPILY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
45	Phosphorylation	LLSFNIESSLGQLNY EEEEECCCCCCCCCH	27.37	22817900
46	Phosphorylation	LSFNIESSLGQLNYE EEEECCCCCCCCCHH	24.59	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UFSP2_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UFSP2_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UFSP2_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of UFSP2_DROME !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UFSP2_DROME

Related Literatures of Post-Translational Modification