UCP6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UCP6_SCHPO
• UniProt AC: Q10187
• Protein Name: UBA domain-containing protein 6
• Gene Name: ucp6
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 612
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Sequence: MEDLDTKIKTLKNMGVSESDAKDSLERCGYDVESAAEFIFSGQLEKSRLVPIMSSTSIASSLPSYQDTFFLPSPRKRRRLPGRIGTVLKPSALFPAIAPFLFVVFEIPVALNTFVHATCKGLLFAEDNASFHRPFTDVSAHLSSSSLSKYNHHSNHRLASPGWWYGEDSCISQSLDPRSVMQVQTIRAFEFLFSSHRLYLDTVHITAALSQVLAGLGNTNTSMSDGDCIAAFLSSYFSPPNAEFDSTFCSTLSSLTNSEKPTYIFNFKPNSTPDLRLSIESCLDLLLHPPSSAQKNWSWIKHVGKVFCCSLPGNNASGTPRFLLTPKIDLSKCIIENRDEMLRRYQLETVYRKTLLEWEDLYKRLTGVTLTDKDIGELLTDGQQFLEKRNPALSSHLQLLKETLQTKISTLISNTNATQHKLSTLYRGMQNKCTRRLLAVIIEPSIIYICLKNSAVQSNRNVSPSANHNEQWYLVRFTTSATISQDSPPCIVEPVTFEEVDLEFEKHISYHNRLLIYVDDDCEASTRTVIPTSVKNFIAEDNEYFDDELAGIIHSPTVSTRSSRSSDVSEYDLEDQGGLQLTVPHINTDVQCHRSRNSACEFPESMHVEHSG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
54	Phosphorylation	SRLVPIMSSTSIASS CCEEEEECCCCHHHC	31.05	27738172
56	Phosphorylation	LVPIMSSTSIASSLP EEEEECCCCHHHCCC	19.49	21712547
57	Phosphorylation	VPIMSSTSIASSLPS EEEECCCCHHHCCCC	20.36	21712547
60	Phosphorylation	MSSTSIASSLPSYQD ECCCCHHHCCCCCCC	30.64	21712547
61	Phosphorylation	SSTSIASSLPSYQDT CCCCHHHCCCCCCCC	34.97	21712547
64	Phosphorylation	SIASSLPSYQDTFFL CHHHCCCCCCCCCCC	40.49	21712547
130	Phosphorylation	LFAEDNASFHRPFTD EECCCCCCCCCCCCH	28.04	21712547
136	Phosphorylation	ASFHRPFTDVSAHLS CCCCCCCCHHHHHHC	37.87	21712547
139	Phosphorylation	HRPFTDVSAHLSSSS CCCCCHHHHHHCCCC	16.87	21712547
143	Phosphorylation	TDVSAHLSSSSLSKY CHHHHHHCCCCHHHC	20.50	25720772
144	Phosphorylation	DVSAHLSSSSLSKYN HHHHHHCCCCHHHCC	30.24	27738172
145	Phosphorylation	VSAHLSSSSLSKYNH HHHHHCCCCHHHCCC	31.74	29996109
146	Phosphorylation	SAHLSSSSLSKYNHH HHHHCCCCHHHCCCC	38.31	29996109
148	Phosphorylation	HLSSSSLSKYNHHSN HHCCCCHHHCCCCCC	34.73	25720772
463	Phosphorylation	VQSNRNVSPSANHNE HCCCCCCCCCCCCCC	19.38	29996109
465	Phosphorylation	SNRNVSPSANHNEQW CCCCCCCCCCCCCCE	33.91	29996109
544	Phosphorylation	FIAEDNEYFDDELAG HHHCCCCCCCCHHHH	20.68	29996109
555	Phosphorylation	ELAGIIHSPTVSTRS HHHHHEECCCCCCCC	16.32	29996109
557	Phosphorylation	AGIIHSPTVSTRSSR HHHEECCCCCCCCCC	30.06	29996109
559	Phosphorylation	IIHSPTVSTRSSRSS HEECCCCCCCCCCCC	22.15	25720772
595	Phosphorylation	TDVQCHRSRNSACEF CCCCCHHCCCCCCCC	16.49	28889911
598	Phosphorylation	QCHRSRNSACEFPES CCHHCCCCCCCCCHH	32.94	29996109
605	Phosphorylation	SACEFPESMHVEHSG CCCCCCHHHCCCCCC	17.90	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UCP6_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UCP6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UCP6_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of UCP6_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-595, AND MASSSPECTROMETRY.
PubMed: 18257517