UBP38_MOUSE - dbPTM
UBP38_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBP38_MOUSE
UniProt AC Q8BW70
Protein Name Ubiquitin carboxyl-terminal hydrolase 38
Gene Name Usp38
Organism Mus musculus (Mouse).
Sequence Length 1042
Subcellular Localization
Protein Description Deubiquitinating enzyme exhibiting a preference towards 'Lys-63'-linked ubiquitin chains..
Protein Sequence MDKILEGLVSSSHPLPLKRMIVRKVVEFAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLQQGYHSVDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPVLCARLSDLLTDFVQCVPKGKLSVTFCQQLVRTIGHFQCVSTQEKELREYVSQVTKVSTLLQNIWKAEPSTLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHVIVPHIVNLVHSFRSDGLPSSTAFLVQLTELVHCMMYHYSGFPDLYEPILEAVKDFPKPSEEKIKLILNQSAWTSQSNALASCLSRLSGKSETGKTGLINLGNTCYMNSVLQALFMATEFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILRVQSSHKPSEGLDCAETCLQEVTSKVAVPTESPGTGDSEKTLIEKMFGGKLRTHICCLNCGSTSHKVEAFTDLSLAFCPSPSVEDLSFQDTASLPSAQDDGLMQTSVADPEEEPVVYNPATAAFVCDSVVNQRVLGSPPVEFHCAESSSVPEESAKILISKDVPQNPGGESTTSVTDLLNYFLAPEVLTGENQYYCESCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRTASFSSLSQSWSVDVDFTDINENLPKKLKPSGTEEAFCPKLVPYLLSSVVVHSGVSSESGHYYSYARNITGTESSYQMCPQSESLALAPSQSCLLGVESPNTVIEQDLENKEMSQEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQSRANGIDSDNPASGVWANGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
71PhosphorylationVLEAYARYHRPEFES
HHHHHHHHHCHHHHH		8.2622871156
78PhosphorylationYHRPEFESFFNKTFV
HHCHHHHHHHCHHHH		40.2222871156
371PhosphorylationSDGLPSSTAFLVQLT
CCCCCCCHHHHHHHH		26.2623608596
483PhosphorylationLNLNGCNSLMKKLQH
CCCCCHHHHHHHHHH		33.64-
541UbiquitinationDRLHEEEKILRVQSS
HHHHHHHHHHHHHCC		50.77-
573PhosphorylationTSKVAVPTESPGTGD
HHCCCCCCCCCCCCC		42.3628066266
575PhosphorylationKVAVPTESPGTGDSE
CCCCCCCCCCCCCCH		30.9825619855
578PhosphorylationVPTESPGTGDSEKTL
CCCCCCCCCCCHHHH		41.0028066266
581PhosphorylationESPGTGDSEKTLIEK
CCCCCCCCHHHHHHH		42.1928066266
584PhosphorylationGTGDSEKTLIEKMFG
CCCCCHHHHHHHHHC		28.9928059163
680PhosphorylationVNQRVLGSPPVEFHC
HHCCCCCCCCEEEEE		23.1325266776
690PhosphorylationVEFHCAESSSVPEES
EEEEECCCCCCCHHH		14.9123984901
691PhosphorylationEFHCAESSSVPEESA
EEEECCCCCCCHHHH		27.1923984901
829PhosphorylationKKLKPSGTEEAFCPK
CCCCCCCCCCCHHHH		34.6830352176
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBP38_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBP38_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBP38_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of UBP38_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBP38_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory