UBE11_ARATH - dbPTM
UBE11_ARATH - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBE11_ARATH
UniProt AC P93028
Protein Name Ubiquitin-activating enzyme E1 1
Gene Name UBA1
Organism Arabidopsis thaliana (Mouse-ear cress).
Sequence Length 1080
Subcellular Localization
Protein Description Activates ubiquitin by first adenylating its C-terminal glycine residue with ATP, and thereafter linking this residue to the side chain of a cysteine residue in E1, yielding a ubiquitin-E1 thioester and free AMP..
Protein Sequence MLHKRASEANDKNDNTIIGSDLASSKKRRIDFTESSSDKSSSILASGSSRGFHGDSVVQQIDMAFGNSNRQEIDEDLHSRQLAVYGRETMRRLFASNVLISGMHGLGAEIAKNLILAGVKSVTLHDERVVELWDLSSNFVFSEDDVGKNRADASVQKLQDLNNAVVVSSLTKSLNKEDLSGFQVVVFSDISMERAIEFDDYCHSHQPPIAFVKADVRGLFGSVFCDFGPEFAVLDVDGEEPHTGIIASISNENQAFISCVDDERLEFEDGDLVVFSEVEGMTELNDGKPRKIKSTRPYSFTLDEDTTNYGTYVKGGIVTQVKQPKLLNFKPLREALKDPGDFLFSDFSKFDRPPLLHLAFQALDHFKAEAGRFPVAGSEEDAQKLISIATAINTGQGDLKVENVDQKLLRHFSFGAKAVLNPMAAMFGGIVGQEVVKACSGKFHPLFQFFYFDSVESLPSEPVDSSDFAPRNSRYDAQISVFGAKFQKKLEDAKVFTVGSGALGCEFLKNLALMGVSCGSQGKLTVTDDDIIEKSNLSRQFLFRDWNIGQAKSTVAASAAAVINPRFNIEALQNRVGAETENVFDDAFWENLTVVVNALDNVNARLYVDSRCLYFQKPLLESGTLGTKCNTQSVIPHLTENYGASRDPPEKQAPMCTVHSFPHNIDHCLTWARSEFEGLLEKTPAEVNAYLSSPVEYTNSMMSAGDAQARDTLERIVECLEKEKCETFQDCLTWARLRFEDYFVNRVKQLIYTFPEDAATSTGAPFWSAPKRFPRPLQYSSSDPSLLNFITATAILRAETFGIPIPEWTKNPKEAAEAVDRVIVPDFEPRQDAKIVTDEKATTLTTASVDDAAVIDDLIAKIDQCRHNLSPDFRMKPIQFEKDDDTNYHMDVIAGLANMRARNYSIPEVDKLKAKFIAGRIIPAIATSTAMATGLVCLELYKVLDGGHKVEAYRNTFANLALPLFSMAEPLPPKVVKHRDMAWTVWDRWVLKGNPTLREVLQWLEDKGLSAYSISCGSCLLFNSMFTRHKERMDKKVVDLARDVAKVELPPYRNHLDVVVACEDEDDNDVDIPLVSIYFR
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
33PhosphorylationKKRRIDFTESSSDKS
CCCCCCCCCCCCCCC
31.0719880383
40PhosphorylationTESSSDKSSSILASG
CCCCCCCCCCEEECC
34.0225561503
41PhosphorylationESSSDKSSSILASGS
CCCCCCCCCEEECCC
27.4325561503
42PhosphorylationSSSDKSSSILASGSS
CCCCCCCCEEECCCC
28.8125561503
46PhosphorylationKSSSILASGSSRGFH
CCCCEEECCCCCCCC
35.4430407730
48PhosphorylationSSILASGSSRGFHGD
CCEEECCCCCCCCCC
17.8625561503
49PhosphorylationSILASGSSRGFHGDS
CEEECCCCCCCCCCH
39.6925561503
520PhosphorylationLMGVSCGSQGKLTVT
HCCCCCCCCCCEEEC
39.8419880383
846PhosphorylationEKATTLTTASVDDAA
CCCCCCEECCCCHHH
21.7623776212
848PhosphorylationATTLTTASVDDAAVI
CCCCEECCCCHHHHH
24.8030291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBE11_ARATH !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBE11_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBE11_ARATH !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of UBE11_ARATH !!

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBE11_ARATH

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Related Literatures of Post-Translational Modification

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