| UniProt ID | UBAC1_MOUSE | |
|---|---|---|
| UniProt AC | Q8VDI7 | |
| Protein Name | Ubiquitin-associated domain-containing protein 1 | |
| Gene Name | Ubac1 | |
| Organism | Mus musculus (Mouse). | |
| Sequence Length | 409 | |
| Subcellular Localization | Cytoplasm. | |
| Protein Description | Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle (By similarity).. | |
| Protein Sequence | MFVQEEKIFAGKVLRLHICAADGAEWLEEATEDTSVEKLKESCLKHGAHGSLEDPKNVTHHKLIHAASERVLSDSKTILEENIQDQDVLLLIKKRVPSPLPKMADVSAEEKKKQEQKAPDKDAILRATANLPACSTDRTAVQTTMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDETALRQLTEMGFPESRASKALRLNHMSVPQAMEWLIEHSEDPAIDTPLPGHAAQAGASAAATTSSTSSEAAVGTSVEDEESRDELTEIFKKIRRKKEFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDQGIDPNSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MFVQEEKI -------CCCCCHHC | 7.19 | - | |
| 19 | Ubiquitination | KVLRLHICAADGAEW CEEEEEEEECCHHHH | 1.45 | 27667366 | |
| 56 | Ubiquitination | HGSLEDPKNVTHHKL CCCCCCCCCCCHHHH | 76.11 | - | |
| 98 | Phosphorylation | LIKKRVPSPLPKMAD HHHHCCCCCCCCCCC | 35.89 | 25521595 | |
| 121 | Ubiquitination | QEQKAPDKDAILRAT HHHHCCCHHHHHHHH | 48.26 | 27667366 | |
| 134 | Glutathionylation | ATANLPACSTDRTAV HHCCCCCCCCCCHHH | 4.20 | 24333276 | |
| 154 | Ubiquitination | DFQTELRKILVSLIE HHHHHHHHHHHHHHH | 53.68 | - | |
| 178 | Ubiquitination | PDAVELFKKANAMLD HHHHHHHHHHHHCCC | 64.70 | - | |
| 179 | Ubiquitination | DAVELFKKANAMLDE HHHHHHHHHHHCCCC | 39.27 | - | |
| 309 | Ubiquitination | MEMGFDEKEVIDALR HHCCCCHHHHHHHHH | 60.16 | - | |
| 334 | Ubiquitination | EWLLGDRKPSPEELD HHHHCCCCCCHHHHH | 55.37 | - | |
| 336 | Phosphorylation | LLGDRKPSPEELDQG HHCCCCCCHHHHHCC | 48.23 | 29899451 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of UBAC1_MOUSE !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of UBAC1_MOUSE !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of UBAC1_MOUSE !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of UBAC1_MOUSE !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
