UB2G1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: UB2G1_MOUSE
• UniProt AC: P62254
• Protein Name: Ubiquitin-conjugating enzyme E2 G1
• Gene Name: Ube2g1
• Organism: Mus musculus (Mouse).
• Sequence Length: 170
• Protein Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4..
• Protein Sequence: MTELQSALLLRRQLAELNKNPVEGFSAGLIDDNDLYRWEVLIIGPPDTLYEGGVFKAHLTFPKDYPLRPPKMKFITEIWHPNVDKNGDVCISILHEPGEDKYGYEKPEERWLPIHTVETIMISVISMLADPNGDSPANVDAAKEWREDRNGEFKRKVARCVRKSQETAFE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MTELQSAL -------CCHHHHHH	6.24	-
2	Acetylation	------MTELQSALL ------CCHHHHHHH	45.46	-
73	Ubiquitination	PLRPPKMKFITEIWH CCCCCCCCEEEEECC	39.48	22790023
101	Ubiquitination	LHEPGEDKYGYEKPE EECCCCCCCCCCCCH	35.95	22790023

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of UB2G1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of UB2G1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of UB2G1_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UBC_MOUSE	Ubc	physical	25471371

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.