dbPTM

UAP1L_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	UAP1L_MOUSE
UniProt AC	Q3TW96
Protein Name	UDP-N-acetylhexosamine pyrophosphorylase-like protein 1
Gene Name	Uap1l1
Organism	Mus musculus (Mouse).
Sequence Length	507
Subcellular Localization
Protein Description
Protein Sequence	MDSERDVRAQLQRAGQDHLLRFYADLAPEARAALLAELASLEADALREHCQRAAAAGALAPGPLPDLAARLQPLPPERVGSAIRCDQETRLRWEEEGFRQISLNKVAVLLLAGGQGTRLGVTYPKGMYQVGLPSQKTLYQLQAERIRRVQQLADQRQGTHCTVPWYIMTSEFTLGPTIKFFKEHDFFHLDPTNVVLFEQRMLPAVTFEGKAILERKDKVAMAPDGNGGLYCALADHQILEDMKQRGVEFVHVYCVDNILVRLADPVFIGFCVLQGADCGAKVVEKAYPEEPVGVVCQVDGVPQVVEYSEISPEIAGQLGADGGLLYNAGNICNHFFTRGFLDVVTREFEPLLRLHVAMKKVPYVDEEGNLVKPLRPNGIKMEKFVFDVFQFAKNFVAFEVCREEEFSPLKNDDTADRDNPSTCRRALLAQHYRWALQAGARFLDVHGVQLTEQSGMLPNGDPPAICEISPLVSYSGEGLEMYLQGRQLQSPFILDEDQARLLRPQDC

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Phosphorylation	-----MDSERDVRAQ -----CCCHHHHHHH	32.98	20531401
50	Glutathionylation	ADALREHCQRAAAAG HHHHHHHHHHHHHHC	2.22	24333276
85	Glutathionylation	RVGSAIRCDQETRLR HCCEEEECCCHHCCC	5.31	24333276
117	Phosphorylation	LLAGGQGTRLGVTYP EECCCCCCEEEEEEC	18.16	20531401
231	Glutathionylation	DGNGGLYCALADHQI CCCCCEEEEEECHHH	2.77	24333276
254	Glutathionylation	VEFVHVYCVDNILVR CCEEEEEEECCHHHH	2.77	24333276
271	Glutathionylation	DPVFIGFCVLQGADC CCEEEEEEEECCCCC	2.23	24333276
278	Glutathionylation	CVLQGADCGAKVVEK EEECCCCCCCEEHHC	5.91	24333276
432	Phosphorylation	RALLAQHYRWALQAG HHHHHHHHHHHHHHC	8.86	20531401
490	Phosphorylation	LQGRQLQSPFILDED CCCCCCCCCCCCCHH	30.30	24453211
507	Glutathionylation	RLLRPQDC------- HHCCCCCC-------	5.17	24333276

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of UAP1L_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of UAP1L_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of UAP1L_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of UAP1L_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of UAP1L_MOUSE

Related Literatures of Post-Translational Modification