U80A2_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: U80A2_ARATH
• UniProt AC: Q9M8Z7
• Protein Name: Sterol 3-beta-glucosyltransferase UGT80A2
• Gene Name: UGT80A2
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 637
• Protein Description: Involved in the biosynthesis of sterol glucosides. Catalyzes the synthesis of steryl glycosides (SGs) and acyl steryl glycosides (ASGs) which are the most abundant sterol derivatives in higher plants. Can act on several sterols like sitosterol, campesterol and stigmasterol. Both UGT80A2 and UGT80B1 are required for the normal production of SGs and ASGs in seeds..
• Protein Sequence: MPEISPAELAKVSSSSSSSSSSSSGRASVKIEEIEGGAAASGVVIVSEELETNPKTVVASIADETVAESSGTGNKSFSRVWTMPLEGSSSSDKAESSSTNQPRLDKSKTERQQKVTHILAEDAAKIFDDKISAGKKLKLLNRIATVKHDGTVEFEVPADAIPQPIVVDRGESKNGVCADESIDGVDLQYIPPMQIVMLIVGTRGDVQPFVAIAKRLQDYGHRVRLATHANFKEFVLTAGLEFYPLGGDPKVLAGYMVKNKGFLPSGPSEIPIQRNQMKDIIYSLLPACKEPDPDSGISFKADAIIANPPAYGHTHVAEALKIPIHVFFTMPWTPTSEFPHPLSRVKQPAGYRLSYQIVDSLIWLGIRDMVNDLRKKKLKLRPVTYLSGTQGSGSNIPHGYMWSPHLVPKPKDWGPQIDVVGFCYLDLASNYEPPAELVEWLEAGDKPIYIGFGSLPVQEPEKMTEIIVEALQRTKQRGIINKGWGGLGNLKEPKDFVYLLDNVPHDWLFPRCKAVVHHGGAGTTAAGLKASCPTTIVPFFGDQPFWGERVHARGVGPSPIPVDEFSLHKLEDAINFMLDDKVKSSAETLAKAMKDEDGVAGAVKAFFKHLPSAKQNISDPIPEPSGFLSFRKCFGCS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Phosphorylation	---MPEISPAELAKV ---CCCCCHHHHHCC		25561503
56	Phosphorylation	ELETNPKTVVASIAD CCCCCCCEEEEEECC		23776212
60	Phosphorylation	NPKTVVASIADETVA CCCEEEEEECCCCHH		23776212
65	Phosphorylation	VASIADETVAESSGT EEEECCCCHHHCCCC		23776212
69	Phosphorylation	ADETVAESSGTGNKS CCCCHHHCCCCCCCC		23776212
70	Phosphorylation	DETVAESSGTGNKSF CCCHHHCCCCCCCCC		23776212
72	Phosphorylation	TVAESSGTGNKSFSR CHHHCCCCCCCCCEE		23776212
76	Phosphorylation	SSGTGNKSFSRVWTM CCCCCCCCCEEEEEE		23776212
78	Phosphorylation	GTGNKSFSRVWTMPL CCCCCCCEEEEEEEC		23776212
82	Phosphorylation	KSFSRVWTMPLEGSS CCCEEEEEEECCCCC		17317660
88	Phosphorylation	WTMPLEGSSSSDKAE EEEECCCCCCCCCCC		23776212
89	Phosphorylation	TMPLEGSSSSDKAES EEECCCCCCCCCCCC		17317660
90	Phosphorylation	MPLEGSSSSDKAESS EECCCCCCCCCCCCC		23776212
91	Phosphorylation	PLEGSSSSDKAESSS ECCCCCCCCCCCCCC		23776212
96	Phosphorylation	SSSDKAESSSTNQPR CCCCCCCCCCCCCCC		23776212
97	Phosphorylation	SSDKAESSSTNQPRL CCCCCCCCCCCCCCC		23776212
98	Phosphorylation	SDKAESSSTNQPRLD CCCCCCCCCCCCCCC		23776212
99	Phosphorylation	DKAESSSTNQPRLDK CCCCCCCCCCCCCCC		23776212
145	Phosphorylation	KLLNRIATVKHDGTV HHHHCEEECCCCCEE		23111157
151	Phosphorylation	ATVKHDGTVEFEVPA EECCCCCEEEEEEEC		23111157
172	Phosphorylation	IVVDRGESKNGVCAD EEEECCCCCCCCCCC		15308754
523	Phosphorylation	VHHGGAGTTAAGLKA EEECCCCCHHHHHHC		25368622
524	Phosphorylation	HHGGAGTTAAGLKAS EECCCCCHHHHHHCC		25368622
531	Phosphorylation	TAAGLKASCPTTIVP HHHHHHCCCCCEEEE		25368622
534	Phosphorylation	GLKASCPTTIVPFFG HHHCCCCCEEEECCC		25368622
535	Phosphorylation	LKASCPTTIVPFFGD HHCCCCCEEEECCCC		25368622

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of U80A2_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of U80A2_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of U80A2_ARATH !!

Protein-Protein Interaction

Oops, there are no PPI records of U80A2_ARATH !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.