dbPTM

U430_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	U430_DROME
UniProt AC	Q9VL63
Protein Name	UPF0430 protein CG31712
Gene Name	CG31712
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	290
Subcellular Localization
Protein Description
Protein Sequence	MGSRSRTPSPSGKRRHHKSKHKKRSKSHHDHERPSTRTDRDKSSEVNNHGRHRERDRDRERDRHRSDRHTERDYRHSPSILKSRKRSSSSSSDSQYSEQESQRSKQKRSRFKKLDEQNQMQVERLAEMERQRRAKELEQKTIEEEAAKRIEMLVKKRVEEELEKRRDEIEQEVNRRVETAKAEMEREMMLELERRREQIREEERRREEDEKQKREELEEILAENNRKIEEAQRKLAEERLAIIEEQRLMDEERQRMRKEQEKRVKEEQKVILGKNNSRPKLSFSLKPGAL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	GSRSRTPSPSGKRRH CCCCCCCCCCCCCCC	30.96	25749252
43	Phosphorylation	TRTDRDKSSEVNNHG CCCCCCCCCCCCCCC	35.70	19429919
44	Phosphorylation	RTDRDKSSEVNNHGR CCCCCCCCCCCCCCC	51.83	19429919
77	Phosphorylation	TERDYRHSPSILKSR HHHHHCCCHHHHHHC	16.02	19429919
79	Phosphorylation	RDYRHSPSILKSRKR HHHCCCHHHHHHCCC	43.50	19429919
83	Phosphorylation	HSPSILKSRKRSSSS CCHHHHHHCCCCCCC	39.32	22817900
282	Phosphorylation	NNSRPKLSFSLKPGA CCCCCCCCEEECCCC	20.93	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of U430_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of U430_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of U430_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of U430_DROME

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of Drosophila melanogaster embryos."; Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.; J. Proteome Res. 7:1675-1682(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77 AND SER-79, AND MASSSPECTROMETRY.	18327897 [Abstract]