U17L7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: U17L7_HUMAN
• UniProt AC: P0C7H9
• Protein Name: Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7
• Gene Name: USP17L7
• Organism: Homo sapiens (Human).
• Sequence Length: 530
• Subcellular Localization: Nucleus. Endoplasmic reticulum.
• Protein Sequence: MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
284	Phosphorylation	ILVLKRFSDVTGNKL HHHHHHHCCCCCCHH	34.89	-
287	Phosphorylation	LKRFSDVTGNKLAKN HHHHCCCCCCHHHCC	39.77	-
368	Phosphorylation	SVLSQQAYVLFYIQK HHHHHCEEEEEEEEH	8.05	-
471	Phosphorylation	LVIHQSKYKCGMKNH EEEECCCCCCCCCCC	19.43	30622161
484	Phosphorylation	NHHPEQQSSLLNLSS CCCHHHHHHHHHCCC	23.73	30622161
485	Phosphorylation	HHPEQQSSLLNLSST CCHHHHHHHHHCCCC	32.32	30622161
495	Phosphorylation	NLSSTKPTDQESMNT HCCCCCCCCHHHCCC	52.44	29978859
499	Phosphorylation	TKPTDQESMNTGTLA CCCCCHHHCCCCCHH	16.23	29978859
502	Phosphorylation	TDQESMNTGTLASLQ CCHHHCCCCCHHHHC	23.93	29978859
504	Phosphorylation	QESMNTGTLASLQGS HHHCCCCCHHHHCCC	19.67	29978859
507	Phosphorylation	MNTGTLASLQGSTRR CCCCCHHHHCCCCCC	25.08	29978859
511	Phosphorylation	TLASLQGSTRRSKGN CHHHHCCCCCCCCCC	13.04	29978859
512	Phosphorylation	LASLQGSTRRSKGNN HHHHCCCCCCCCCCC	36.61	29978859

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of U17L7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of U17L7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of U17L7_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of U17L7_HUMAN !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.