dbPTM

TXLNA_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TXLNA_MOUSE
UniProt AC	Q6PAM1
Protein Name	Alpha-taxilin
Gene Name	Txlna
Organism	Mus musculus (Mouse).
Sequence Length	554
Subcellular Localization
Protein Description	May be involved in intracellular vesicle traffic and potentially in calcium-dependent exocytosis in neuroendocrine cells..
Protein Sequence	MKNQDKKNGPAKHSNSKGSPGQREAGPEGAHGRPRQTAPGAEAEGSTSQAPGKTEGARAKAAQPGALCDVSEELSRQLEDILSTYCVDNNQGGPAEEGAQGEPTEPEDTEKSRTYAARNGEPEPGIPVVNGEKETSKGEPGTEEIRASDEVGDRDHRRPQEKKKAKGLGKEITLLMQTLNTLSTPEEKLAALCKKYAELLEEHRNSQKQMKLLQKKQSQLVQEKDHLRGEHSKAVLARSKLESLCRELQRHNRSLKEEGVQRAREEEEKRKEVTSHFQVTLNDIQLQMEQHNERNSKLRQENMELAERLKKLIEQYELREEHIDKVFKHKDLQQQLVDAKLQQAQEMLKEAEERHQREKEFLLKEAVESQRMCELMKQQETHLKQQLALYTEKFEEFQNTLSKSSEVFTTFKQEMEKMTKKIKKLEKETTMYRSRWESSNKALLEMAEEKTVRDKELEGLQVKIQRLEKLCRALQTERNDLNKRVQDLTAGGITDIGSERRPEATTASKEQGVESPGAQPASSPRATDAPCCSGAPSTGTAGQTGPGEPTPATA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Acetylation	DKKNGPAKHSNSKGS CCCCCCCCCCCCCCC	51.18	19849233
19	Phosphorylation	KHSNSKGSPGQREAG CCCCCCCCCCCCCCC	29.59	25266776
37	Phosphorylation	AHGRPRQTAPGAEAE CCCCCCCCCCCCCCC	35.78	23375375
71	Phosphorylation	PGALCDVSEELSRQL CCCCCCCCHHHHHHH	16.47	-
195	Acetylation	KLAALCKKYAELLEE HHHHHHHHHHHHHHH	49.01	22826441
243	Phosphorylation	LARSKLESLCRELQR HHHHHHHHHHHHHHH	43.11	24719451
515	Phosphorylation	SKEQGVESPGAQPAS CHHHCCCCCCCCCCC	26.65	25521595
522	Phosphorylation	SPGAQPASSPRATDA CCCCCCCCCCCCCCC	47.78	27087446
523	Phosphorylation	PGAQPASSPRATDAP CCCCCCCCCCCCCCC	22.10	27087446
527	Phosphorylation	PASSPRATDAPCCSG CCCCCCCCCCCCCCC	33.69	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TXLNA_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TXLNA_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TXLNA_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TXLNA_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TXLNA_MOUSE

Related Literatures of Post-Translational Modification