TV23C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TV23C_HUMAN
• UniProt AC: Q96ET8
• Protein Name: Golgi apparatus membrane protein TVP23 homolog C
• Gene Name: TVP23C
• Organism: Homo sapiens (Human).
• Sequence Length: 276
• Subcellular Localization: Membrane ; Multi-pass membrane protein .
• Protein Sequence: MLQQDSNDDTEDVSLFDAEEETTNRPRKAKIRHPVASFFHLFFRVSAIIVCLLCELLSSSFITCMVTIILLLSCDFWAVKNVTGRLMVGLRWWNHIDEDGKSHWVFESRKESSQENKTVSEAESRIFWLGLIACSVLWVIFAFSALFSFTVKWLRRSRHIAQTGLKVLGSRDPPASAFQSAGITGVSRCPGHPSRKFHQVDINSFTRITDRALYWKPAPRLSSPPLRAAPGNCQQMAPARLFLSLRLWAWRGGGESPNSRGTGEPGPKFHLASGMH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MLQQDSND -------CCCCCCCC		19413330
6	Phosphorylation	--MLQQDSNDDTEDV --CCCCCCCCCCCCC		29255136
10	Phosphorylation	QQDSNDDTEDVSLFD CCCCCCCCCCCCCCC		29255136
14	Phosphorylation	NDDTEDVSLFDAEEE CCCCCCCCCCCCCHH		29255136
22	Phosphorylation	LFDAEEETTNRPRKA CCCCCHHCCCCCCHH		20639409
23	Phosphorylation	FDAEEETTNRPRKAK CCCCHHCCCCCCHHH		20639409
110	Ubiquitination	HWVFESRKESSQENK EEEEECCCCCCCCCC		-
117	Ubiquitination	KESSQENKTVSEAES CCCCCCCCCHHHHHH		21906983
117 (in isoform 1)	Ubiquitination	-		21906983
117 (in isoform 2)	Ubiquitination	-		21906983
120	Phosphorylation	SQENKTVSEAESRIF CCCCCCHHHHHHHHH		27499020
124	Phosphorylation	KTVSEAESRIFWLGL CCHHHHHHHHHHHHH		22964224
170	Phosphorylation	TGLKVLGSRDPPASA HCCEECCCCCCCCHH		-
180	Ubiquitination	PPASAFQSAGITGVS CCCHHHHHCCCCCCC		29967540
192	Ubiquitination	GVSRCPGHPSRKFHQ CCCCCCCCCCCCCEE		21890473
192 (in isoform 3)	Ubiquitination	-		-
222	Phosphorylation	WKPAPRLSSPPLRAA CCCCCCCCCCCCCCC		26699800
223	Phosphorylation	KPAPRLSSPPLRAAP CCCCCCCCCCCCCCC		23927012

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TV23C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TV23C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TV23C_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TV23C_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.