TUTLA_HUMAN - dbPTM
TUTLA_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TUTLA_HUMAN
UniProt AC Q9P2J2
Protein Name Protein turtle homolog A
Gene Name IGSF9
Organism Homo sapiens (Human).
Sequence Length 1179
Subcellular Localization Cell membrane
Single-pass type I membrane protein. Cell junction, synapse. Enriched at the excitatory synapses in mature neurons..
Protein Description Functions in dendrite outgrowth and synapse maturation..
Protein Sequence MVWCLGLAVLSLVISQGADGRGKPEVVSVVGRAGESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELVPKRLDGYVLEGRQGSQGWEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPSNTANVSTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAGCLLNRRRAARRRRKRLRQDPPLIFSPTGKSAAPSALGSGSPDSVAKLKLQGSPVPSLRQSLLWGDPAGTPSPHPDPPSSRGPLPLEPICRGPDGRFVMGPTVAAPQERSGREQAEPRTPAQRLARSFDCSSSSPSGAPQPLCIEDISPVAPPPAAPPSPLPGPGPLLQYLSLPFFREMNVDGDWPPLEEPSPAAPPDYMDTRRCPTSSFLRSPETPPVSPRESLPGAVVGAGATAEPPYTALADWTLRERLLPGLLPAAPRGSLTSQSSGRGSASFLRPPSTAPSAGGSYLSPAPGDTSSWASGPERWPRREHVVTVSKRRNTSVDENYEWDSEFPGDMELLETLHLGLASSRLRPEAEPELGVKTPEEGCLLNTAHVTGPEARCAALREEFLAFRRRRDATRARLPAYRQPVPHPEQATLL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
81PhosphorylationSPRIDPDYVGRVRLQ
CCCCCCCCCCEEEEE		15.3628348404
92PhosphorylationVRLQKGASLQIEGLR
EEEECCCEEEEECEE		29.4928348404
106PhosphorylationRVEDQGWYECRVFFL
EECCCCEEEEEEEEE		16.3928348404
188N-linked_GlycosylationQGQVQVQNGTLRIRR
CCEEEEECCEEEEEE		46.70UniProtKB CARBOHYD
256N-linked_GlycosylationHAEAYPANLTYSWFQ
ECEEECCCCCEEEHH		28.54UniProtKB CARBOHYD
513N-linked_GlycosylationTSPHVVTNVSVVALP
CCCCCEEEEEEEECC		16.68UniProtKB CARBOHYD
524N-linked_GlycosylationVALPKGANVSWEPGF
EECCCCCCCCCCCCC		36.70UniProtKB CARBOHYD
625PhosphorylationTEIPPPLSPPRGLVA
CCCCCCCCCCCCEEE		38.3424719451
635PhosphorylationRGLVAVRTPRGVLLH
CCEEEEEECCEEEEE		15.67-
782PhosphorylationQDPPLIFSPTGKSAA
CCCCEEECCCCCCCC		17.9824719451
784PhosphorylationPPLIFSPTGKSAAPS
CCEEECCCCCCCCCH		56.9230266825
787PhosphorylationIFSPTGKSAAPSALG
EECCCCCCCCCHHHC		30.8927732954
791PhosphorylationTGKSAAPSALGSGSP
CCCCCCCHHHCCCCC		31.2530266825
795PhosphorylationAAPSALGSGSPDSVA
CCCHHHCCCCCCCHH		36.6325849741
797PhosphorylationPSALGSGSPDSVAKL
CHHHCCCCCCCHHHH		27.5130266825
800PhosphorylationLGSGSPDSVAKLKLQ
HCCCCCCCHHHHEEC		27.6230266825
809PhosphorylationAKLKLQGSPVPSLRQ
HHHEECCCCCCCHHH		15.1230266825
813PhosphorylationLQGSPVPSLRQSLLW
ECCCCCCCHHHHHHC		36.1030266825
817PhosphorylationPVPSLRQSLLWGDPA
CCCCHHHHHHCCCCC		20.9924719451
826PhosphorylationLWGDPAGTPSPHPDP
HCCCCCCCCCCCCCC		23.7727732954
828PhosphorylationGDPAGTPSPHPDPPS
CCCCCCCCCCCCCCC		35.3627732954
835PhosphorylationSPHPDPPSSRGPLPL
CCCCCCCCCCCCCCC		37.7527732954
836PhosphorylationPHPDPPSSRGPLPLE
CCCCCCCCCCCCCCC		47.2127732954
965PhosphorylationTRRCPTSSFLRSPET
CCCCCCHHHCCCCCC		30.6724719451
969PhosphorylationPTSSFLRSPETPPVS
CCHHHCCCCCCCCCC		29.2730266825
972PhosphorylationSFLRSPETPPVSPRE
HHCCCCCCCCCCCHH		35.9630266825
976PhosphorylationSPETPPVSPRESLPG
CCCCCCCCCHHCCCC		24.8230266825
1020PhosphorylationLPAAPRGSLTSQSSG
CCCCCCCCCCCCCCC		29.7424719451
1025PhosphorylationRGSLTSQSSGRGSAS
CCCCCCCCCCCCCCE		34.2328348404
1026PhosphorylationGSLTSQSSGRGSASF
CCCCCCCCCCCCCEE		25.5228348404
1032PhosphorylationSSGRGSASFLRPPST
CCCCCCCEECCCCCC		26.8924719451
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TUTLA_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TUTLA_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TUTLA_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TUTLA_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TUTLA_HUMAN

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Related Literatures of Post-Translational Modification

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