dbPTM

TTI1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TTI1_SCHPO
UniProt AC	O94600
Protein Name	TEL2-interacting protein 1
Gene Name	tti1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	1098
Subcellular Localization	Cytoplasm .
Protein Description	Component of the TORC1 and TORC2 complexes required for the regulation of the cellular respons to changes in available nutrients..
Protein Sequence	MSHIQSIFAQIRDPFRKLSFYSLPLSSETSSVDSNGLKNSLKDAYFGLEKALTNTDADLPLNLCDYIFFPIVPVLKSWYRVPSTGVEYAIQCVNLLYKHGWREAHNEMLTMQLLLMLLNIADGWKSPSETVEQDFRVREITFETLENVITDFKPNFHDKRQYLLFARALSSALDIIPNKNSSRRLQFASLCCVQKLICPKQYRLPTEFLTTFLPGIVSGLTKGLAPNGTCQYFKNVCISLNILGDTVVKAISDDNTKDLPDEKDASSNSHFFGPTKRTKSWKRATCQQLSNAVKAILHLRSSQNLHVQDALFDFCFILFRDCLDSLKDCRIHLLESMLKLINKKENPKLRDYGMNKLVSLIESFNNITMESVLTECLNDWSTTWSSVSTFASEDNKLEELNRLKSLLSISSHLPKTLQLMEPLLDGILSQLVPKSSGIDSNSQKLLTSSTSNEYIHGEFFGGNEMERTTQEIVTSFAKAPNVKYVMQSLLSKATSATNENSVRAFWAFMVLLKSDVETVDSLEMYIDSLEQYSFEVLQQLSQLNVFTKASLEDKQKKEKYNLLCVRSCIAIDSISWISSLQGVKFRSKLMAYFYPLLEHLAFASPYVSSFAEACIQAIATNCNYSTPAELLRENIDYVVNSVALKLNTLDVSPQLPIVMAYVIKNDDGGCIRYIGDVVDAIFGILDAYHGYARLTEGLLGILYAIIKQESINGEEKKLIVGVEEDAMNEDKNKPCKKIREFVQLLLENPNYPLPKDDHELEDMIHDEQQETKSGHEQFREHAMKEKEKKGKENENMGETTVDHENINSNVMDEQGEKQKDDVVDMVRKITEKAQLFLSHEQITIRVEMLKLLSYGSNVLAKEPNTFYPAINTFWPLVVIQLDTDNELLVECALETIYQVCALADDFMTSRIRQDLLPRLETLCQRWHLFNVARTYSSEHRLQRAMLKVTSACVANKLSIVVYLKLMGITAPIIRAITHMSQKYAGDESLVEETWNAFSKQNPDAVYYEREVRGSQMIDTFSTELLIPGKQRVQRTYRRTHEVLEPVGAKTSETVFNDLLGQQGSGKTETQEEPLPSLDNLLHLNQPKKGAKKPLISII

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
19	Phosphorylation	RDPFRKLSFYSLPLS CCHHHHCEEEECCCC	25.77	25720772
21	Phosphorylation	PFRKLSFYSLPLSSE HHHHCEEEECCCCCC	13.11	25720772
22	Phosphorylation	FRKLSFYSLPLSSET HHHCEEEECCCCCCC	22.85	25720772
710	Phosphorylation	YAIIKQESINGEEKK HHHHHHHCCCCCCEE	20.89	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TTI1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TTI1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TTI1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TTI1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TTI1_SCHPO

Related Literatures of Post-Translational Modification