dbPTM

TTC27_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TTC27_MOUSE
UniProt AC	Q8CD92
Protein Name	Tetratricopeptide repeat protein 27
Gene Name	Ttc27
Organism	Mus musculus (Mouse).
Sequence Length	847
Subcellular Localization
Protein Description
Protein Sequence	MPGMMWTPELALLRGFSTEAERLVWKQEGICGSDIGVFLELLLEGSYEALFFHSTTQTILNSTMMAEEKIDSYLEKQIVNFLDCSTDLEEIERQQLVFLLGVSSLQLFVQSNWTGPLVDLHPQDFLPSGLLEQFSEVKGLDAIIMGLLILDGESVYSLTSKPILLLIARIILVNIRHKLTALQSLPWWTLRYVNIHQQLLEERSPQLFALAKNCIDQVMKQENLFEGDSGRLLAIQFHLECAHVFLYYYEYKEAKDQFSTAKDISKLEIDLTGALGKRTRFQENYVAQLIVDVRRKEAVPFSCEFSPAPTPQECLAKNLELNDDTVLNEIKLADSERFQMPDLCAEELAVVLGVCTNFQKNNPVHKLTEEELLAFTSCLLSQPKFWAIQMSALILRTKLERGSTRRVERAMRQTQALADQFEDKATSVLERLKIFYCCQVPPHWAVQRQLAGLLFELGCTSSALQIFEKLEMWEDVVICHERAGRHGKAEEILRQELEKKETPGLYCLLGDVLQDHSCYDKAWELSRHRSARAQRSKALLHLRNKEFRECVECFERSVKINPMQLGVWFSLGCAYLALEDYGGSAKAFQRCVTLEPDNAEAWNNLSTSYIRLKQKVKAFRTLQEALKCNYEHWQIWENYILTSTDVGEFGEAIKAYHRLLDLRDKYKDIQVLKILVQAVVNDMTDRSGAVASSLKGKLQELFGRITSRVTNDGEVWRLYAQVHGNGQSEKPDENDKAFQCLSKAYKCDTQSSCWEKDATAFKEVVQRAIGLAHVAMKCAESKSIPQEAVQTLSSVRLNLRGLLSKAKQNFTDVVSGEVSGELASEIAAVNALEAELQDLSNQLRNRY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
259	Phosphorylation	KEAKDQFSTAKDISK HHHHHHHCCHHHHHH	23.09	25338131
262	Ubiquitination	KDQFSTAKDISKLEI HHHHCCHHHHHHCEE	56.54	27667366
384	Acetylation	SCLLSQPKFWAIQMS HHHHCCCCHHHHHHH	45.99	19861607

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TTC27_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TTC27_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TTC27_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TTC27_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TTC27_MOUSE

Related Literatures of Post-Translational Modification