TTC1_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTC1_MOUSE
• UniProt AC: Q91Z38
• Protein Name: Tetratricopeptide repeat protein 1
• Gene Name: Ttc1
• Organism: Mus musculus (Mouse).
• Sequence Length: 292
• Protein Sequence: MEEKSEDCKVPEDLFNGLKVADPQEGESASPMVSDPKGQHCQSKLPKAAEAHPQDDHVEEECFHDCSASFEEEQPGAHVAGSKASDDSSSELDEEYLIELEKNMPEEEKQKRREESAKLKEEGNERFKRGDYMEAESSYSQALQMCPACFQKDRSVLFSNRAAARMKQDKKETAITDCSKAIQLNPTYIRAILRRAELYEKTDKLDEALEDYKSVLEKDPSVHQAREACMRLPKQIEERNERLKEEMLGKLKDLGNLVLRPFGLSTENFQIKQDSSTGSYSINFVQNPNNNR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
28	Phosphorylation	ADPQEGESASPMVSD CCCCCCCCCCCCCCC	44.92	28066266
30	Phosphorylation	PQEGESASPMVSDPK CCCCCCCCCCCCCCC	23.86	26824392
34	Phosphorylation	ESASPMVSDPKGQHC CCCCCCCCCCCCCCH	41.78	28066266
67	Phosphorylation	EECFHDCSASFEEEQ HHHHCCCCCCCCCCC	32.76	25266776
69	Phosphorylation	CFHDCSASFEEEQPG HHCCCCCCCCCCCCC	19.52	30635358
82	Phosphorylation	PGAHVAGSKASDDSS CCCCCCCCCCCCCCC	18.47	25777480
85	Phosphorylation	HVAGSKASDDSSSEL CCCCCCCCCCCCCCC	45.76	25619855
88	Phosphorylation	GSKASDDSSSELDEE CCCCCCCCCCCCCHH	40.53	25619855
89	Phosphorylation	SKASDDSSSELDEEY CCCCCCCCCCCCHHH	34.52	25619855
90	Phosphorylation	KASDDSSSELDEEYL CCCCCCCCCCCHHHH	46.24	25619855
96	Phosphorylation	SSELDEEYLIELEKN CCCCCHHHHHHHHHC	15.78	25619855
178	Glutathionylation	KETAITDCSKAIQLN CHHHHHHHHHHHHCC	3.17	24333276
221	Phosphorylation	SVLEKDPSVHQAREA HHHHHCCCHHHHHHH	42.22	29514104
265	Phosphorylation	VLRPFGLSTENFQIK EEEECCCCCCCEEEE	33.77	26824392
266	Phosphorylation	LRPFGLSTENFQIKQ EEECCCCCCCEEEEE	39.74	26643407

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTC1_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTC1_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTC1_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TTC1_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.