dbPTM

TTC17_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TTC17_MOUSE
UniProt AC	E9PVB5
Protein Name	Tetratricopeptide repeat protein 17
Gene Name	Ttc17
Organism	Mus musculus (Mouse).
Sequence Length	1198
Subcellular Localization	Cytoplasm. Cell membrane. Cytoplasm, cytoskeleton. Localized with CATIP at F-actin rich zones and at dynamic plasma membrane protrusions..
Protein Description	Plays a role in primary ciliogenesis by modulating actin polymerization..
Protein Sequence	MAAAIGVRGRFELLPRSGPGWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALDDSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPGFEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFGGTLEMKGRRLDLQGIRVLKKGPQDGVAKSSCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
522	Phosphorylation	LGGELPTYFLPPENK CCCCCCCEECCCCCC	-
814	Phosphorylation	ESTVVEESNGSDEVE EEEEEECCCCCCCCC	29899451
920	Phosphorylation	PGKKVEASQAENGQR CCCCCCHHHCCCCCE	21454597
928	Phosphorylation	QAENGQRYQANLEIT HCCCCCEEEEEEEEE	21454597
935	Phosphorylation	YQANLEITGPKVASP EEEEEEEECCCCCCC	21454597

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TTC17_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TTC17_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TTC17_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TTC17_MOUSE !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TTC17_MOUSE

Related Literatures of Post-Translational Modification