TTC13_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TTC13_HUMAN
• UniProt AC: Q8NBP0
• Protein Name: Tetratricopeptide repeat protein 13
• Gene Name: TTC13
• Organism: Homo sapiens (Human).
• Sequence Length: 860
• Protein Sequence: MAPAGCCCCCCFWGGAVAAAGAARRVLLLLLLGVLSAGLRPGALATEHYSPLSLLKQELQHRQQQEAPAGGGGCSPQSGDWGDQYSAECGESSFLNFHDSDCEPKGSSPCDSLLSLNTEKILSQAKSIAEQKRFPFATDNDSTNEELAIAYVLIGSGLYDEAIRHFSTMLQEEPDLVSAIYGRGIAYGKKGLHDIKNAELALFELSRVITLEPDRPEVFEQRAEILSPLGRINEAVNDLTKAIQLQPSARLYRHRGTLYFISEDYATAHEDFQQSLELNKNQPIAMLYKGLTFFHRGLLKEAIESFKEALKQKVDFIDAYKSLGQAYRELGNFEAATESFQKALLLNQNHVQTLQLRGMMLYHHGSLQEALKNFKRCLQLEPYNEVCQYMKGLSHVAMGQFYEGIKAQTKVMLNDPLPGQKASPEYLKVKYLREYSRYLHAHLDTPLTEYNIDVDLPGSFKDHWAKNLPFLIEDYEEQPGLQPHIKDVLHQNFESYKPEVQELICVADRLGSLMQYETPGFLPNKRIHRAMGLAALEVMQAVQRTWTNSKVRMNGKTRLMQWRDMFDIAVKWRRIADPDQPVLWLDQMPARSLSRGFNNHINLIRGQVINMRYLEYFEKILHFIKDRILVYHGANNPKGLLEVREALEKVHKVEDLLPIMKQFNTKTKDGFTVNTKVPSLKDQGKEYDGFTITITGDKVGNILFSVETQTTEERTQLYHAEIDALYKDLTAKGKVLILSSEFGEADAVCNLILSLVYYFYNLMPLSRGSSVIAYSVIVGALMASGKEVAGKIPKGKLVDFEAMTAPGSEAFSKVAKSWMNLKSISPSYKTLPSVSETFPTLRSMIEVLNTDSSPRCLKKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
36	Phosphorylation	LLLLGVLSAGLRPGA HHHHHHHHCCCCCCC	20.20	30622161
53	Phosphorylation	TEHYSPLSLLKQELQ HCCCCHHHHHHHHHH	34.73	24719451
120	Ubiquitination	LLSLNTEKILSQAKS HHHCCHHHHHHHHHH	47.08	-
126	Ubiquitination	EKILSQAKSIAEQKR HHHHHHHHHHHHHCC	34.46	-
206	Phosphorylation	ELALFELSRVITLEP HHHHHHHHHCEECCC	19.80	20058876
307	Ubiquitination	KEAIESFKEALKQKV HHHHHHHHHHHHHCC	51.89	-
313	Ubiquitination	FKEALKQKVDFIDAY HHHHHHHCCCHHHHH	42.03	-
321	Ubiquitination	VDFIDAYKSLGQAYR CCHHHHHHHHHHHHH	40.71	-
322	Phosphorylation	DFIDAYKSLGQAYRE CHHHHHHHHHHHHHH	25.67	27251275
362	Phosphorylation	QLRGMMLYHHGSLQE HHHHHHHHCCCCHHH	3.63	28509920
366	Phosphorylation	MMLYHHGSLQEALKN HHHHCCCCHHHHHHH	23.63	28509920
394	Phosphorylation	CQYMKGLSHVAMGQF HHHHHCCCHHHHHHH	25.28	28509920
402	Phosphorylation	HVAMGQFYEGIKAQT HHHHHHHHHHHHHHC	12.83	28509920
409	Phosphorylation	YEGIKAQTKVMLNDP HHHHHHHCEEECCCC	30.39	25262027
421	Ubiquitination	NDPLPGQKASPEYLK CCCCCCCCCCHHHHH	57.66	-
423	Phosphorylation	PLPGQKASPEYLKVK CCCCCCCCHHHHHHH	25.87	21815630
428	Ubiquitination	KASPEYLKVKYLREY CCCHHHHHHHHHHHH	35.46	-
466	Ubiquitination	SFKDHWAKNLPFLIE CCHHHHHHHCCEEEE	54.55	-
547	Phosphorylation	QAVQRTWTNSKVRMN HHHHHHHCCCCCCCC	29.06	24719451
549	Phosphorylation	VQRTWTNSKVRMNGK HHHHHCCCCCCCCCE	25.75	24719451
638	Ubiquitination	YHGANNPKGLLEVRE ECCCCCHHHHHHHHH	65.40	-
649	Ubiquitination	EVREALEKVHKVEDL HHHHHHHHHHCHHHH	50.95	-
661	Ubiquitination	EDLLPIMKQFNTKTK HHHHHHHHHHCCCCC	53.08	-
668	Ubiquitination	KQFNTKTKDGFTVNT HHHCCCCCCCCEEEC	58.36	-
676	Ubiquitination	DGFTVNTKVPSLKDQ CCCEEECCCCCHHHC	47.12	-
681	Ubiquitination	NTKVPSLKDQGKEYD ECCCCCHHHCCCEEC	52.95	-
727	Ubiquitination	AEIDALYKDLTAKGK HHHHHHHHHHCCCCC	47.30	-
796	Ubiquitination	AGKIPKGKLVDFEAM CCCCCCCCCCCEEEE	52.00	-
804	O-linked_Glycosylation	LVDFEAMTAPGSEAF CCCEEEECCCCCHHH	36.43	OGP
812	O-linked_Glycosylation	APGSEAFSKVAKSWM CCCCHHHHHHHHHHH	33.01	OGP
823	Phosphorylation	KSWMNLKSISPSYKT HHHHCCCCCCCCCCC	31.31	-
837	Phosphorylation	TLPSVSETFPTLRSM CCCCHHHHHHHHHHH	27.66	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TTC13_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TTC13_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TTC13_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of TTC13_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.