TT21A_HUMAN - dbPTM
TT21A_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TT21A_HUMAN
UniProt AC Q8NDW8
Protein Name Tetratricopeptide repeat protein 21A
Gene Name TTC21A
Organism Homo sapiens (Human).
Sequence Length 1320
Subcellular Localization
Protein Description
Protein Sequence MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAISDLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFLWLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLKKIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVVGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
7Phosphorylation-MSSNDSSLMAGIIY
-CCCCHHCHHHHHHH		25.6528509920
99PhosphorylationEAIQELEYSLKEIRK
HHHHHHHHHHHHHHH		31.7426852163
100PhosphorylationAIQELEYSLKEIRKT
HHHHHHHHHHHHHHH		24.4824719451
255PhosphorylationIDACQILTVHELARE
CCHHHEEHHHHHHHC		22.8023532336
266PhosphorylationLAREGNMTTVSSLKT
HHHCCCCCCHHHHHH		28.22-
267PhosphorylationAREGNMTTVSSLKTQ
HHCCCCCCHHHHHHH		13.9728258704
270PhosphorylationGNMTTVSSLKTQKAT
CCCCCHHHHHHHHHH		29.5528258704
273PhosphorylationTTVSSLKTQKATNHV
CCHHHHHHHHHHHHH		40.3628258704
277PhosphorylationSLKTQKATNHVRNLI
HHHHHHHHHHHHHHH		32.6624114839
306PhosphorylationLKKIIVVSRLCGSHQ
HHHHHHHHHHCCCHH		14.5124719451
326PhosphorylationVCSFIERTFMATPSY
HHHHHHHHHCCCCCH		12.6525404012
330PhosphorylationIERTFMATPSYVHVA
HHHHHCCCCCHHHHH		10.8628634298
332PhosphorylationRTFMATPSYVHVATE
HHHCCCCCHHHHHHH		35.1228634298
333PhosphorylationTFMATPSYVHVATEL
HHCCCCCHHHHHHHC		8.8625404012
338PhosphorylationPSYVHVATELGYLFI
CCHHHHHHHCCHHHH		30.5628634298
342PhosphorylationHVATELGYLFILKNQ
HHHHHCCHHHHCHHH		15.8625404012
357PhosphorylationVKEALLWYSEAMKLD
HHHHHHHHHHHHCCC		9.1527134283
358PhosphorylationKEALLWYSEAMKLDK
HHHHHHHHHHHCCCC		13.8027134283
481PhosphorylationRLPGQIVSPLLKQVA
CCCCCCCHHHHHHHH		16.0924719451
691PhosphorylationRNILPKQSCYMEARE
HHHCCCCCHHHHHHH		17.2228509920
693PhosphorylationILPKQSCYMEAREKM
HCCCCCHHHHHHHHH		11.8428509920
704PhosphorylationREKMANIYLQTLRDR
HHHHHHHHHHHHHHH		7.8030301811
707PhosphorylationMANIYLQTLRDRRLY
HHHHHHHHHHHHHHH		22.5930301811
751PhosphorylationPEKALEVYDEAYRQN
HHHHHHHHHHHHHHC		9.9322210691
778PhosphorylationAYVKAHQYTEAIEYY
HHHHHHHHHHHHHHH		9.18-
858PhosphorylationKKEAVIETLNKALDL
CHHHHHHHHHHHHHH		25.22-
883PhosphorylationEQPEMIPSQKQLAAS
CCCCCCCCHHHHHHH		38.8030622161
1022PhosphorylationELAKKVSSRVPLEPG
HHHHHHHCCCCCCCC		40.0422468782
1149PhosphorylationNMEAALGSFIQIAQA
CHHHHHHHHHHHHHH		21.7430622161
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TT21A_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TT21A_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TT21A_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TT21A_HUMAN !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TT21A_HUMAN

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Related Literatures of Post-Translational Modification

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