TSSK3_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TSSK3_MOUSE
• UniProt AC: Q9D2E1
• Protein Name: Testis-specific serine/threonine-protein kinase 3
• Gene Name: Tssk3
• Organism: Mus musculus (Mouse).
• Sequence Length: 268
• Protein Description: May be involved in a signaling pathway during male germ cell development or mature sperm function..
• Protein Sequence: MEDFLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKIIDKMGGPEEFIQRFLPRELQIVRTLDHKNIIQVYEMLESADGKIYLVMELAEGGDVFDCVLNGGPLPESRAKALFRQMVEAIRYCHGCGVAHRDLKCENALLQGFNLKLTDFGFAKVLPKSRRELSQTFCGSTAYAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLWQQQKGVSFPTHLGISTECQDLLKRLLEPDMILRPSIEEVSWHPWLAST

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
166	Phosphorylation	PKSRRELSQTFCGST CCCHHHHHHHHCCCH	23.56	22817900
168	Phosphorylation	SRRELSQTFCGSTAY CHHHHHHHHCCCHHH	19.95	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
166	S	Phosphorylation	Kinase	TSSK3	Q9D2E1	PSP
168	T	Phosphorylation	Kinase	PDPK1	O15530	GPS
168	T	Phosphorylation	Kinase	PDK1	Q9Z2A0	GPS

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TSSK3_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TSSK3_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TSSK3_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.