TSR1_MOUSE - dbPTM
TSR1_MOUSE - PTM Information in dbPTM
Basic Information of Protein
UniProt ID TSR1_MOUSE
UniProt AC Q5SWD9
Protein Name Pre-rRNA-processing protein TSR1 homolog
Gene Name Tsr1
Organism Mus musculus (Mouse).
Sequence Length 803
Subcellular Localization Nucleus, nucleolus.
Protein Description Required during maturation of the 40S ribosomal subunit in the nucleolus..
Protein Sequence MAAHRSGPLKQQNKAHKGGRHHGGGSAQRDSKGRVGPKILCKKLKRQLSRIDQRHRASQLRKQKRESVLAEKRQLGSKDGPPHQVLVVPLHSRISLPEAFKLLQNEDLGTVYLSERGSTQSFMLLCPSLKHRWFFTYARPGDLHTLLDMAKVADTILFLLDPLEGWDSTGDYCLSCLFAQGLPTYTLAVQGLSGFPPKKQIDARKKLSKMVEKRFPEDKLLLLDTQQESGMLLRQLANQKQRHLAFRDRRAYLFAHVADFVPSEESDLVGTLKISGYVRGRTLNVNSLLHIVGHGDFQMNQIDAPVDPFPLNPRVIKSQKKPNMAMEVCVTDAAPDMEEDLKVLMKADPDHQESLQTEAIPDPMEGEQTWPTEEELDEADDLLKQRSRVVKKVPKGTSSYQAEWILDEGDESDGEGGEYDDIQHEGFMEEESQDGSGEEEEEECETMTLGESVRDDLYDEKVDAEDEERMLEKYKQERLEEMFPDEMDTPRDVAARIRFQKYRGLKSFRTSPWDPKENLPRDYARIFQFQNFVNTRKRIFKEIEEKEAEGAEVGWYVTLHVSDVPVSVVEYFRQGAPLIAFSLLPYEQKMSVLNMVVSRNPGNTEPVKAKEELIFHCGFRRFRASPLFSQHTAADKHKFQRFLTADAAFVVTVFAPITFPPASVLLFKQRRNGMHSLIATGHLFSVDPDRMVIKRVVLSGHPFKIFTKMAVVRYMFFNREDVMWFKPVELRTKWGRRGHIKEPLGTHGHMKCSFDGKLKSQDTVLMNLYKRVFPKWTYDPYVPEPVPWVKSDISSTVSEVDME
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
49PhosphorylationKKLKRQLSRIDQRHR
HHHHHHHHHHHHHHH		20.8923970565
67PhosphorylationLRKQKRESVLAEKRQ
HHHHHHHHHHHHHHH		26.8529176673
118PhosphorylationVYLSERGSTQSFMLL
EEEECCCCCCEEECC		29.5130635358
119PhosphorylationYLSERGSTQSFMLLC
EEECCCCCCEEECCC		30.9330635358
121PhosphorylationSERGSTQSFMLLCPS
ECCCCCCEEECCCCC		16.8330635358
199AcetylationLSGFPPKKQIDARKK
CCCCCCHHHHHHHHH		59.257613137
205AcetylationKKQIDARKKLSKMVE
HHHHHHHHHHHHHHH		60.847613147
206AcetylationKQIDARKKLSKMVEK
HHHHHHHHHHHHHHH		53.067613157
489PhosphorylationMFPDEMDTPRDVAAR
HCCCCCCCHHHHHHH		20.9325338131
591PhosphorylationLPYEQKMSVLNMVVS
CCHHHHHHHHHHHHC		30.4120139300
726AcetylationREDVMWFKPVELRTK
HHHCEEEEEEEEECC		32.4222826441
763PhosphorylationGKLKSQDTVLMNLYK
CCCCCCCCHHHHHHH		14.1125177544
769PhosphorylationDTVLMNLYKRVFPKW
CCHHHHHHHHHCCCC		7.5525177544
791PhosphorylationEPVPWVKSDISSTVS
CCCCCCCCCHHCCCC		30.4725619855
794PhosphorylationPWVKSDISSTVSEVD
CCCCCCHHCCCCCCC		25.5823684622
795PhosphorylationWVKSDISSTVSEVDM
CCCCCHHCCCCCCCC		32.9125619855
796PhosphorylationVKSDISSTVSEVDME
CCCCHHCCCCCCCCC		22.6625619855
798PhosphorylationSDISSTVSEVDME--
CCHHCCCCCCCCC--		31.8023684622
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of TSR1_MOUSE !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of TSR1_MOUSE !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of TSR1_MOUSE !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions

Oops, there are no PPI records of TSR1_MOUSE !!
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of TSR1_MOUSE

loading...

Related Literatures of Post-Translational Modification

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory