| UniProt ID | TSN10_HUMAN | |
|---|---|---|
| UniProt AC | Q9H1Z9 | |
| Protein Name | Tetraspanin-10 | |
| Gene Name | TSPAN10 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 355 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein . |
|
| Protein Description | Regulates maturation of the transmembrane metalloprotease ADAM10.. | |
| Protein Sequence | MEEGERSPLLSQETAGQKPLSVHRPPTSGCLGPVPREDQAEAWGCSCCPPETKHQALSGTPKKGPAPSLSPGSSCVKYLIFLSNFPFSLLGLLALAIGLWGLAVKGSLGSDLGGPLPTDPMLGLALGGLVVSAASLAGCLGALCENTCLLRGFSGGILAFLVLEAVAGALVVALWGPLQDSLEHTLRVAIAHYQDDPDLRFLLDQVQLGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCCIDPREDGASVNDQCGFGVLRLDADAAQRVVYLEGCGPPLRRWLRANLAASGGYAIAVVLLQGAELLLAARLLGALAARSGAAYGPGAHGEDRAGPQSPSPGAPPAAKPARG | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MEEGERSPLLSQET -CCCCCCCCCCCCCC | 18.65 | 22199227 | |
| 11 | Phosphorylation | GERSPLLSQETAGQK CCCCCCCCCCCCCCC | 33.38 | 29514088 | |
| 14 | Phosphorylation | SPLLSQETAGQKPLS CCCCCCCCCCCCCCC | 28.57 | 29514088 | |
| 21 | Phosphorylation | TAGQKPLSVHRPPTS CCCCCCCCCCCCCCC | 25.14 | 25159151 | |
| 60 | Phosphorylation | KHQALSGTPKKGPAP CCHHHCCCCCCCCCC | 28.67 | 25159151 | |
| 107 | Phosphorylation | WGLAVKGSLGSDLGG HHHHHHCCCCCCCCC | 24.68 | - | |
| 110 | Phosphorylation | AVKGSLGSDLGGPLP HHHCCCCCCCCCCCC | 34.65 | - | |
| 118 | Phosphorylation | DLGGPLPTDPMLGLA CCCCCCCCCHHHHHH | 61.49 | - | |
| 228 | N-linked_Glycosylation | WQQNLYFNCSSPGVQ HHHHEEEECCCCCCC | 15.94 | UniProtKB CARBOHYD | |
| 341 | Phosphorylation | EDRAGPQSPSPGAPP CCCCCCCCCCCCCCC | 30.40 | 22199227 | |
| 343 | Phosphorylation | RAGPQSPSPGAPPAA CCCCCCCCCCCCCCC | 41.01 | 26425664 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TSN10_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TSN10_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TSN10_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ADA10_HUMAN | ADAM10 | physical | 23091066 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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