dbPTM

TSK_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TSK_HUMAN
UniProt AC	Q8WUA8
Protein Name	Tsukushin
Gene Name	TSKU
Organism	Homo sapiens (Human).
Sequence Length	353
Subcellular Localization	Secreted .
Protein Description
Protein Sequence	MPWPLLLLLAVSGAQTTRPCFPGCQCEVETFGLFDSFSLTRVDCSGLGPHIMPVPIPLDTAHLDLSSNRLEMVNESVLAGPGYTTLAGLDLSHNLLTSISPTAFSRLRYLESLDLSHNGLTALPAESFTSSPLSDVNLSHNQLREVSVSAFTTHSQGRALHVDLSHNLIHRLVPHPTRAGLPAPTIQSLNLAWNRLHAVPNLRDLPLRYLSLDGNPLAVIGPGAFAGLGGLTHLSLASLQRLPELAPSGFRELPGLQVLDLSGNPKLNWAGAEVFSGLSSLQELDLSGTNLVPLPEALLLHLPALQSVSVGQDVRCRRLVREGTYPRRPGSSPKVALHCVDTRDSAARGPTIL

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
12	Phosphorylation	LLLLLAVSGAQTTRP HHHHHHHCCCCCCCC	23.86	24043423
16	Phosphorylation	LAVSGAQTTRPCFPG HHHCCCCCCCCCCCC	25.00	24043423
17	Phosphorylation	AVSGAQTTRPCFPGC HHCCCCCCCCCCCCC	22.12	24043423
74	N-linked_Glycosylation	SNRLEMVNESVLAGP CCHHHCCCHHHHCCC	34.22	UniProtKB CARBOHYD
109	Phosphorylation	TAFSRLRYLESLDLS CHHHHHHHHHHCCCC	21.29	-
131	Phosphorylation	PAESFTSSPLSDVNL CHHHHCCCCCCCCCC	27.14	-
137	N-linked_Glycosylation	SSPLSDVNLSHNQLR CCCCCCCCCCCHHCE	40.59	UniProtKB CARBOHYD
152	O-linked_Glycosylation	EVSVSAFTTHSQGRA EEEEEEEEECCCCCE	24.26	55835747
153	O-linked_Glycosylation	VSVSAFTTHSQGRAL EEEEEEEECCCCCEE	17.05	55835753
248	O-linked_Glycosylation	RLPELAPSGFRELPG CCHHHCCCCCCCCCC	44.98	55833721

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TSK_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TSK_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TSK_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TSK_HUMAN !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TSK_HUMAN

Related Literatures of Post-Translational Modification