dbPTM

TRPE_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TRPE_SCHPO
UniProt AC	O94582
Protein Name	Probable anthranilate synthase component 1
Gene Name	trp3
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	489
Subcellular Localization
Protein Description
Protein Sequence	MKIYPDLKQVQELAEKHKANKIPIYGVIPADMLTPSVAYLKLNQGKKYSFILESVTQGESVSRYSFIGSPYRILMANGKTDPLARLERELKEVKTAPVEGLPSFSGGAVGYVSYDCIKYFEPTTEMPLEDTLGLPEAMFFMTDDLVAFDHAYQTVKIISHVCIQQGRPIEEAYEAAVFKINMLKKKLESPEIPLPEQKKVHLGYEAKSNVGEDGYKAFVSNLKEHIFNGDIFQAVPSQRIARRTDLHPFNLYRHLRTVNPSPYMFYIHCDDFDIIGASPELLVKSEHGRIINHPIAGTVPRGKTKEEDEAYAKDLLASVKDRAEHVMLVDLARNDVSRVCDLDTTSVDKLMTIEKFSHVQHLVSQVSGVLRPDKTRFDAFRSIFPAGTVSGSPKVRAIQLVYGLEKEKRGIYAGAVGRWGYEDDNMDTCIAIRTMVYKDGTVYLQAGGGIVFDSDEQDEYVETLNKLRSNVTAIEETEKLYAEEENSSA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
390	Phosphorylation	IFPAGTVSGSPKVRA HCCCCCCCCCCHHHH	33.13	28889911
392	Phosphorylation	PAGTVSGSPKVRAIQ CCCCCCCCCHHHHHH	17.65	28889911
469	Phosphorylation	ETLNKLRSNVTAIEE HHHHHHHHCCHHHHH	46.19	21712547
472	Phosphorylation	NKLRSNVTAIEETEK HHHHHCCHHHHHHHH	26.60	21712547
487	Phosphorylation	LYAEEENSSA----- HHHHHHCCCC-----	30.81	25720772
488	Phosphorylation	YAEEENSSA------ HHHHHCCCC------	49.97	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TRPE_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TRPE_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TRPE_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TRPE_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TRPE_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-390; SER-392 ANDSER-488, AND MASS SPECTROMETRY.	18257517 [Abstract]