TRM1L_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TRM1L_MOUSE
• UniProt AC: A2RSY6
• Protein Name: TRMT1-like protein
• Gene Name: Trmt1l
• Organism: Mus musculus (Mouse).
• Sequence Length: 728
• Protein Description: May play a role in motor coordination and exploratory behavior..
• Protein Sequence: MENMAEEELLPQEKEEAQVRVPTPAPDSAPVPAPAADTALDSAPTPDSDPAPALAPAPAPALSPSLASVPEEAESKRHISIQRRLADLEKLAFGTEGDVDSASSLNSDNPGTENSQTCPLCPKEKFRAYSSHKLRRHLQNLHWKISVEFEGYRMCICHLACRPVKPTIVGEQISSKLGAHYHCIICSATITRRTDMLGHVKRHVNKGETKSRYIAASTAKSSNEILKETDTDIQVFPNYSIPQKTDSYFNPKMKLNRQIIFCTLAALAKERKPLECLDAFGATGIMGLQWAKHLGNAVKVTINDLNENSVTLIQKNCHLNKLKVVVDSEEKEEGDALEDDGTLGDIQVTRMDANVLMHLRSFDFIHLDPFGTSVNYLDSAFRNVRNLGIVSVTSTDISSLYAKAQHVARRHYGCNIVRTEYYKELAARIVVAAVARAAARCNKGIEVLFAVALEHFVLVVVRVLRGPTSADETAKKIQYLIHCQWCEERIFQKDGNMVEENPYRQLPCNCHGSMPGKTAIELGPLWSSSLFNTGFLKRMLFESIHHGLDDIQPLIKTLIFESECTPQSQCSTHAPSNTNKQEENGVFVKTTDDTTIDIYSAQGKRKSNEMAINLAKKQKTDASTAHPPFYYNIHRHSIKGMNMPKLKKFLCCLSQAGFRVSRTHFDPMGIRTDAPLMQFKSILLKYSTPTYTGAQSEGQMPPAAEDTVTDRVEMSVSDKAEASGCRRW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	Phosphorylation	EAQVRVPTPAPDSAP HHCCCCCCCCCCCCC	29.26	19060867
28	Phosphorylation	VPTPAPDSAPVPAPA CCCCCCCCCCCCCCC	33.15	25338131
45	Phosphorylation	TALDSAPTPDSDPAP CCHHCCCCCCCCCCC	39.17	25338131
48	Phosphorylation	DSAPTPDSDPAPALA HCCCCCCCCCCCCCC	46.85	21189417
63	Phosphorylation	PAPAPALSPSLASVP CCCCCCCCHHHHCCC	17.97	22817900
65	Phosphorylation	PAPALSPSLASVPEE CCCCCCHHHHCCCHH	32.94	25338131
75	Phosphorylation	SVPEEAESKRHISIQ CCCHHHHHHHHHCHH	41.88	21189417
220	Ubiquitination	YIAASTAKSSNEILK HHHHHHCCCHHHHHH	55.28	22790023
328	Phosphorylation	KLKVVVDSEEKEEGD CEEEEEECCHHHCCC	35.72	30635358
391	Phosphorylation	VRNLGIVSVTSTDIS CCCCCEEEEECCCHH	20.11	21454597
401	Phosphorylation	STDISSLYAKAQHVA CCCHHHHHHHHHHHH	14.17	21454597
606	Ubiquitination	YSAQGKRKSNEMAIN EECCCCCHHHHHHHH	62.21	-
607	Phosphorylation	SAQGKRKSNEMAINL ECCCCCHHHHHHHHH	41.89	25266776
637	Phosphorylation	YYNIHRHSIKGMNMP CCEEHHHCCCCCCCH	26.42	22817900

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TRM1L_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TRM1L_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TRM1L_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TRM1L_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.