dbPTM

TRIPB_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TRIPB_HUMAN
UniProt AC	Q15643
Protein Name	Thyroid receptor-interacting protein 11
Gene Name	TRIP11
Organism	Homo sapiens (Human).
Sequence Length	1979
Subcellular Localization	Golgi apparatus, cis-Golgi network membrane Peripheral membrane protein . Cytoplasm, cytoskeleton . Associates with the ends of centrosome-nucleated microtubules.
Protein Description	Binds the ligand binding domain of the thyroid receptor (THRB) in the presence of triiodothyronine and enhances THRB-modulated transcription. Golgi auto-antigen; probably involved in maintaining cis-Golgi structure..
Protein Sequence	MSSWLGGLGSGLGQSLGQVGGSLASLTGQISNFTKDMLMEGTEEVEAELPDSRTKEIEAIHAILRSENERLKKLCTDLEEKHEASEIQIKQQSTSYRNQLQQKEVEISHLKARQIALQDQLLKLQSAAQSVPSGAGVPATTASSSFAYGISHHPSAFHDDDMDFGDIISSQQEINRLSNEVSRLESEVGHWRHIAQTSKAQGTDNSDQSEICKLQNIIKELKQNRSQEIDDHQHEMSVLQNAHQQKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIEELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQKQLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNHLQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQSKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQDIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKLLNEKNISLTKQIDQLSKDEVGKLTQIIQQKDLEIQALHARISSTSHTQDVVYLQQQLQAYAMEREKVFAVLNEKTRENSHLKTEYHKMMDIVAAKEAALIKLQDENKKLSTRFESSGQDMFRETIQNLSRIIREKDIEIDALSQKCQTLLAVLQTSSTGNEAGGVNSNQFEELLQERDKLKQQVKKMEEWKQQVMTTVQNMQHESAQLQEELHQLQAQVLVDSDNNSKLQVDYTGLIQSYEQNETKLKNFGQELAQVQHSIGQLCNTKDLLLGKLDIISPQLSSASLLTPQSAECLRASKSEVLSESSELLQQELEELRKSLQEKDATIRTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEKALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQVESLQEQLNVVSKQRDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLEGKVISLQECLDEANAALDSASRLTEQLDVKEEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKVLMRNLFIGHFHTPKNQRHEVLRLMGSILGVRREEMEQLFHDDQGGVTRWMTGWLGGGSKSVPNTPLRPNQQSVVNSSFSELFVKFLETESHPSIPPPKLSVHDMKPLDSPGRRKRDTNAPESFKDTAESRSGRRTDVNPFLAPRSAAVPLINPAGLGPGGPGHLLLKPISDVLPTFTPLPALPDNSAGVVLKDLLKQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSSWLGGLG ------CCCCCCCCC	41.34	25944712
2	Phosphorylation	------MSSWLGGLG ------CCCCCCCCC	41.34	-
3	Phosphorylation	-----MSSWLGGLGS -----CCCCCCCCCC	37.87	-
42	Phosphorylation	KDMLMEGTEEVEAEL HHHHHCCCCHHHHCC	18.70	30576142
55	Ubiquitination	ELPDSRTKEIEAIHA CCCCCCHHHHHHHHH	56.43	29967540
66	Phosphorylation	AIHAILRSENERLKK HHHHHHHCCHHHHHH	41.13	30576142
73	Acetylation	SENERLKKLCTDLEE CCHHHHHHHCCHHHH	54.08	7696051
93	Phosphorylation	EIQIKQQSTSYRNQL HHHHHHHHHHHHHHH	19.48	24043423
94	Phosphorylation	IQIKQQSTSYRNQLQ HHHHHHHHHHHHHHH	25.99	24043423
95	Phosphorylation	QIKQQSTSYRNQLQQ HHHHHHHHHHHHHHH	27.60	24043423
96	Phosphorylation	IKQQSTSYRNQLQQK HHHHHHHHHHHHHHC	17.42	24043423
110	Ubiquitination	KEVEISHLKARQIAL CCHHHHHHHHHHHHH	3.56	29967540
111	Ubiquitination	EVEISHLKARQIALQ CHHHHHHHHHHHHHH	35.78	29967540
169	Phosphorylation	MDFGDIISSQQEINR CCHHHHHHCHHHHHH	23.56	29978859
170	Phosphorylation	DFGDIISSQQEINRL CHHHHHHCHHHHHHH	26.02	29978859
178	Phosphorylation	QQEINRLSNEVSRLE HHHHHHHHHHHHHHH	27.92	29978859
182	Phosphorylation	NRLSNEVSRLESEVG HHHHHHHHHHHHHHC	25.60	29978859
184	Ubiquitination	LSNEVSRLESEVGHW HHHHHHHHHHHHCCH	7.09	22817900
186	Ubiquitination	NEVSRLESEVGHWRH HHHHHHHHHHCCHHH	42.02	22817900
226	Phosphorylation	KELKQNRSQEIDDHQ HHHHHCCCCCCCHHH	39.45	28985074
237	Phosphorylation	DDHQHEMSVLQNAHQ CHHHHHHHHHHHHHH	19.38	28555341
248	Phosphorylation	NAHQQKLTEISRRHR HHHHHHHHHHHHHHH	38.00	23836654
251	Phosphorylation	QQKLTEISRRHREEL HHHHHHHHHHHHHHH	19.61	24670416
259	Phosphorylation	RRHREELSDYEERIE HHHHHHHHHHHHHHH	41.23	20873877
261	Phosphorylation	HREELSDYEERIEEL HHHHHHHHHHHHHHH	19.13	20873877
277	Phosphorylation	NLLQQGGSGVIETDL HHHHCCCCCCHHCCH	36.39	-
296	Ubiquitination	EMQKTIQVLQIEKVE HHHHHHHEEEEEEHH	3.62	22817900
299	Ubiquitination	KTIQVLQIEKVESTK HHHHEEEEEEHHHCH	4.90	22817900
343	2-Hydroxyisobutyrylation	QEQLNVEKRQIMEEC HHHHCHHHHHHHHHH	45.37	-
383	Phosphorylation	RILAQSASVEEVFRL HHHHHCCCHHHHHHH	35.00	26471730
395	Phosphorylation	FRLQQALSDAENEIM HHHHHHHHHHHHHHH	37.48	28348404
405	Phosphorylation	ENEIMRLSSLNQDNS HHHHHHHHHCCCCCC	23.55	-
406	Phosphorylation	NEIMRLSSLNQDNSL HHHHHHHHCCCCCCH	35.61	22199227
412	Phosphorylation	SSLNQDNSLAEDNLK HHCCCCCCHHHHHHH	36.93	21815630
417	Ubiquitination	DNSLAEDNLKLKMRI CCCHHHHHHHHHHHH	30.49	24816145
418	Ubiquitination	NSLAEDNLKLKMRIE CCHHHHHHHHHHHHH	12.14	22817900
419	Ubiquitination	SLAEDNLKLKMRIEV CHHHHHHHHHHHHHH	52.93	21906983
420	Ubiquitination	LAEDNLKLKMRIEVL HHHHHHHHHHHHHHH	6.25	22817900
421	Ubiquitination	AEDNLKLKMRIEVLE HHHHHHHHHHHHHHH	25.25	22817900
432	Phosphorylation	EVLEKEKSLLSQEKE HHHHHHHHHHHHCHH	35.32	28348404
444	Phosphorylation	EKEELQMSLLKLNNE CHHHHHHHHHHHCCC	20.00	24719451
452	Phosphorylation	LLKLNNEYEVIKSTA HHHHCCCHHHHHHHC	20.02	28796482
460	Phosphorylation	EVIKSTATRDISLDS HHHHHHCCCCCCCCH	29.03	-
464	Phosphorylation	STATRDISLDSELHD HHCCCCCCCCHHHHH	30.34	29255136
467	Phosphorylation	TRDISLDSELHDLRL CCCCCCCHHHHHHHH	47.56	23663014
486	Phosphorylation	KEQELNQSISEKETL HHHHHHHCCCHHHHH	27.32	19664994
488	Phosphorylation	QELNQSISEKETLIA HHHHHCCCHHHHHHH	48.11	23663014
492	Phosphorylation	QSISEKETLIAEIEE HCCCHHHHHHHHHHH	34.24	18669648
503	Ubiquitination	EIEELDRQNQEATKH HHHHHHHCCHHHHHH	56.47	22817900
506	Ubiquitination	ELDRQNQEATKHMIL HHHHCCHHHHHHHHH	66.89	22817900
508	Phosphorylation	DRQNQEATKHMILIK HHCCHHHHHHHHHHH	22.26	27251275
527	Phosphorylation	KQQNEGDSIISKLKQ HCCCCHHHHHHHHHH	32.45	21815630
530	Phosphorylation	NEGDSIISKLKQDLN CCHHHHHHHHHHHCC	30.20	27794612
556	Ubiquitination	DKMDITKELDVQKEK HCCCHHHHHHHHHHH	41.37	22817900
595	Phosphorylation	LVDQLNKSQESNVSI HHHHHHHHHHHCCCH	37.80	25159151
596	Ubiquitination	VDQLNKSQESNVSIQ HHHHHHHHHHCCCHH	60.80	23000965
601	Phosphorylation	KSQESNVSIQKENLE HHHHHCCCHHHHHHH	24.45	25159151
602	Ubiquitination	SQESNVSIQKENLEL HHHHCCCHHHHHHHH	6.21	23000965
621	Phosphorylation	RQNEEELSRIRNELM HHCHHHHHHHHHHHH	29.01	28258704
624	Ubiquitination	EEELSRIRNELMQSL HHHHHHHHHHHHHHH	29.47	24816145
630	Phosphorylation	IRNELMQSLNQDSNS HHHHHHHHHCCCCCC	18.47	29978859
635	Phosphorylation	MQSLNQDSNSNFKDT HHHHCCCCCCCHHHH	32.18	29978859
637	Phosphorylation	SLNQDSNSNFKDTLL HHCCCCCCCHHHHHH	47.82	29978859
642	Phosphorylation	SNSNFKDTLLKEREA CCCCHHHHHHHHHHH	34.28	29978859
659	Phosphorylation	RNLKQNLSELEQLNE HHHHHHHHHHHHHHH	47.92	25599653
737	Ubiquitination	KRLLEEANKYEKTIE HHHHHHHHHHHHHHH	51.20	22817900
738	Ubiquitination	RLLEEANKYEKTIEE HHHHHHHHHHHHHHH	62.93	22817900
740	Ubiquitination	LEEANKYEKTIEELS HHHHHHHHHHHHHHH	45.38	22817900
741	Ubiquitination	EEANKYEKTIEELSN HHHHHHHHHHHHHHH	52.27	22817900
754	Phosphorylation	SNARNLNTSALQLEH HHCCCCCCCHHHHHH	20.67	29214152
755	Phosphorylation	NARNLNTSALQLEHE HCCCCCCCHHHHHHH	26.38	25159151
763	Ubiquitination	ALQLEHEHLIKLNQK HHHHHHHHHHHHHHH	34.46	22817900
771	Acetylation	LIKLNQKKDMEIAEL HHHHHHHHHHHHHHH	53.17	22424773
779	Acetylation	DMEIAELKKNIEQMD HHHHHHHHHHHHHHC	34.97	22424773
787	Phosphorylation	KNIEQMDTDHKETKD HHHHHHCCCCHHHHH	34.36	29083192
792	Phosphorylation	MDTDHKETKDVLSSS HCCCCHHHHHHHHCC	37.03	29083192
799	Phosphorylation	TKDVLSSSLEEQKQL HHHHHHCCHHHHHHH	36.10	26437602
803	Ubiquitination	LSSSLEEQKQLTQLI HHCCHHHHHHHHHHH	29.44	23000965
807	Phosphorylation	LEEQKQLTQLINKKE HHHHHHHHHHHHHHH	20.88	26270265
809	Ubiquitination	EQKQLTQLINKKEIF HHHHHHHHHHHHHHH	3.82	23000965
812	Acetylation	QLTQLINKKEIFIEK HHHHHHHHHHHHHHH	44.80	25953088
812	Malonylation	QLTQLINKKEIFIEK HHHHHHHHHHHHHHH	44.80	32601280
813	Malonylation	LTQLINKKEIFIEKL HHHHHHHHHHHHHHH	52.10	26320211
847	Phosphorylation	KNEILRQTIEEKDRS HCHHHHHHHHHHHHC	24.75	22210691
858	Ubiquitination	KDRSLGSMKEENNHL HHHCCCCHHHHHHHH	6.34	24816145
859	Ubiquitination	DRSLGSMKEENNHLQ HHCCCCHHHHHHHHH	64.67	24816145
887	Phosphorylation	APVADPKTLDSVTEL CCCCCHHHHHHHHHH	40.98	23879269
890	Phosphorylation	ADPKTLDSVTELASE CCHHHHHHHHHHHHH	33.77	27251275
892	Phosphorylation	PKTLDSVTELASEVS HHHHHHHHHHHHHHH	29.27	27251275
917	Ubiquitination	EEIKHHQKIIEDQNQ HHHHHHHHHHHHHHH	41.09	24816145
965	Ubiquitination	FLEKDEEIKSLQKTI HHHCHHHHHHHHHHH	3.27	33845483
966	Ubiquitination	LEKDEEIKSLQKTIE HHCHHHHHHHHHHHH	48.68	33845483
969	Ubiquitination	DEEIKSLQKTIEQIK HHHHHHHHHHHHHHH	48.19	29967540
970	Ubiquitination	EEIKSLQKTIEQIKT HHHHHHHHHHHHHHH	57.68	29967540
975	Ubiquitination	LQKTIEQIKTQLHEE HHHHHHHHHHHHHHH	3.19	32015554
976	Ubiquitination	QKTIEQIKTQLHEER HHHHHHHHHHHHHHH	29.88	32015554
991	Phosphorylation	QDIQTDNSDIFQETK HHHCCCCCCHHHHHC	34.59	24719451
997	Ubiquitination	NSDIFQETKVQSLNI CCCHHHHHCCEEEEC	26.23	22817900
998	Ubiquitination	SDIFQETKVQSLNIE CCHHHHHCCEEEECC	37.21	22817900
1001	Phosphorylation	FQETKVQSLNIENGS HHHHCCEEEECCCCC	26.77	28348404
1008	Phosphorylation	SLNIENGSEKHDLSK EEECCCCCCCCCCCH	55.86	17192257
1009	Ubiquitination	LNIENGSEKHDLSKA EECCCCCCCCCCCHH	56.67	33845483
1010	Ubiquitination	NIENGSEKHDLSKAE ECCCCCCCCCCCHHH	44.08	33845483
1037	Ubiquitination	LEIKLLNEKNISLTK HHHHHHHHCCCCHHH	47.66	23000965
1038	Ubiquitination	EIKLLNEKNISLTKQ HHHHHHHCCCCHHHH	59.51	23000965
1041	Phosphorylation	LLNEKNISLTKQIDQ HHHHCCCCHHHHHHH	39.10	24719451
1043	Ubiquitination	NEKNISLTKQIDQLS HHCCCCHHHHHHHCC	17.70	23000965
1044	Ubiquitination	EKNISLTKQIDQLSK HCCCCHHHHHHHCCH	51.02	-
1044	Ubiquitination	EKNISLTKQIDQLSK HCCCCHHHHHHHCCH	51.02	23000965
1055	Ubiquitination	QLSKDEVGKLTQIIQ HCCHHHHHHHHHHHH	19.74	33845483
1056	Ubiquitination	LSKDEVGKLTQIIQQ CCHHHHHHHHHHHHH	54.24	33845483
1086	Phosphorylation	SHTQDVVYLQQQLQA CCCHHHHHHHHHHHH	9.91	22817900
1100	2-Hydroxyisobutyrylation	AYAMEREKVFAVLNE HHHHHHHHHHHHHCH	49.20	-
1124	Ubiquitination	TEYHKMMDIVAAKEA HHHHHHHHHHHHHHH	28.81	24816145
1145	Phosphorylation	DENKKLSTRFESSGQ HCCCCHHHHHHHCCH	50.22	21712546
1149	Phosphorylation	KLSTRFESSGQDMFR CHHHHHHHCCHHHHH	36.74	21712546
1168	Ubiquitination	NLSRIIREKDIEIDA HHHHHHHHCCCCHHH	44.67	29967540
1169	Ubiquitination	LSRIIREKDIEIDAL HHHHHHHCCCCHHHH	54.91	29967540
1267	Phosphorylation	NSKLQVDYTGLIQSY CCEEEEEEHHHHHHH	12.12	22817900
1274	Phosphorylation	YTGLIQSYEQNETKL EHHHHHHHHHCHHHH	12.73	25022875
1279	Phosphorylation	QSYEQNETKLKNFGQ HHHHHCHHHHHHHHH	49.58	25022875
1279	Ubiquitination	QSYEQNETKLKNFGQ HHHHHCHHHHHHHHH	49.58	29967540
1280	Ubiquitination	SYEQNETKLKNFGQE HHHHCHHHHHHHHHH	51.81	29967540
1313	Phosphorylation	LGKLDIISPQLSSAS HCCCCCCCCCCCCCC	13.61	28348404
1318	Phosphorylation	IISPQLSSASLLTPQ CCCCCCCCCCCCCCC	30.39	28348404
1320	Phosphorylation	SPQLSSASLLTPQSA CCCCCCCCCCCCCCH	26.34	28348404
1323	Phosphorylation	LSSASLLTPQSAECL CCCCCCCCCCCHHHH	25.28	24719451
1326	Phosphorylation	ASLLTPQSAECLRAS CCCCCCCCHHHHHHC	27.52	27251275
1333	Phosphorylation	SAECLRASKSEVLSE CHHHHHHCHHHHHHC	30.22	24719451
1333	Ubiquitination	SAECLRASKSEVLSE CHHHHHHCHHHHHHC	30.22	32015554
1334	Ubiquitination	AECLRASKSEVLSES HHHHHHCHHHHHHCH	50.04	32015554
1335	Phosphorylation	ECLRASKSEVLSESS HHHHHCHHHHHHCHH	30.37	29496963
1339	Phosphorylation	ASKSEVLSESSELLQ HCHHHHHHCHHHHHH	40.38	28348404
1341	Phosphorylation	KSEVLSESSELLQQE HHHHHHCHHHHHHHH	26.24	25849741
1342	Phosphorylation	SEVLSESSELLQQEL HHHHHCHHHHHHHHH	28.36	21712546
1355	Phosphorylation	ELEELRKSLQEKDAT HHHHHHHHHHHCHHH	28.93	24732914
1358	Ubiquitination	ELRKSLQEKDATIRT HHHHHHHHCHHHHHH	59.19	24816145
1359	2-Hydroxyisobutyrylation	LRKSLQEKDATIRTL HHHHHHHCHHHHHHH	39.44	-
1359	Ubiquitination	LRKSLQEKDATIRTL HHHHHHHCHHHHHHH	39.44	24816145
1362	Phosphorylation	SLQEKDATIRTLQEN HHHHCHHHHHHHHHC	22.56	24732914
1374	Phosphorylation	QENNHRLSDSIAATS HHCCCHHCHHCHHHH	29.30	21712546
1376	Phosphorylation	NNHRLSDSIAATSEL CCCHHCHHCHHHHHH	15.68	28555341
1399	Methylation	DSEIKQLKEKQDVLQ HHHHHHHHHHHHHHH	61.44	-
1412	2-Hydroxyisobutyrylation	LQKLLKEKDLLIKAK HHHHHHHCCHHHHHC	52.68	-
1412	Acetylation	LQKLLKEKDLLIKAK HHHHHHHCCHHHHHC	52.68	25953088
1432	Ubiquitination	SSNENFTNKVNENEL CCCCCCCCCCCHHHH	41.98	29967540
1433	Ubiquitination	SNENFTNKVNENELL CCCCCCCCCCHHHHH	43.30	29967540
1475	Acetylation	IVETYRGKETEYQAL HHHHHCCCHHHHHHH	53.09	7972651
1477	Phosphorylation	ETYRGKETEYQALQE HHHCCCHHHHHHHHH	43.40	20068231
1479	Phosphorylation	YRGKETEYQALQETN HCCCHHHHHHHHHHC	13.40	20068231
1485	Phosphorylation	EYQALQETNMKFSMM HHHHHHHHCCCHHHH	27.87	20068231
1490	Phosphorylation	QETNMKFSMMLREKE HHHCCCHHHHHHHCH	9.58	20068231
1504	Acetylation	EFECHSMKEKALAFE HHCCCCHHHHHHHHH	60.11	20167786
1522	Phosphorylation	KEKEQGKTGELNQLL HHHHCCCHHHHHHHH	42.59	20068231
1660	Phosphorylation	DETALQLSVSQEQVK CCCHHHHCCCHHHHH	13.53	27251275
1770	Phosphorylation	DVQKKLMSLANSSEG HHHHHHHHHHCCCCC	34.46	21406692
1774	Phosphorylation	KLMSLANSSEGKVDK HHHHHHCCCCCCCCH	24.94	21406692
1775	Phosphorylation	LMSLANSSEGKVDKV HHHHHCCCCCCCCHH	50.61	21406692
1794	Phosphorylation	LFIGHFHTPKNQRHE HHCCCCCCCHHHHHH	34.71	28555341
1808	Phosphorylation	EVLRLMGSILGVRRE HHHHHHHHHHCCCHH	10.73	20068231
1833	Phosphorylation	GGVTRWMTGWLGGGS CCCHHHCCCCCCCCC	20.46	22985185
1840	Phosphorylation	TGWLGGGSKSVPNTP CCCCCCCCCCCCCCC	25.65	27422710
1841	Phosphorylation	GWLGGGSKSVPNTPL CCCCCCCCCCCCCCC	59.76	32142685
1842	Phosphorylation	WLGGGSKSVPNTPLR CCCCCCCCCCCCCCC	44.50	29255136
1845	Phosphorylation	GGSKSVPNTPLRPNQ CCCCCCCCCCCCCCC	52.77	32142685
1846	Phosphorylation	GSKSVPNTPLRPNQQ CCCCCCCCCCCCCCH	20.03	25463755
1854	Phosphorylation	PLRPNQQSVVNSSFS CCCCCCHHHHCCCHH	20.47	29255136
1858	Phosphorylation	NQQSVVNSSFSELFV CCHHHHCCCHHHHHH	22.58	29255136
1859	Phosphorylation	QQSVVNSSFSELFVK CHHHHCCCHHHHHHH	27.82	25159151
1861	Phosphorylation	SVVNSSFSELFVKFL HHHCCCHHHHHHHHH	35.02	22617229
1870	Phosphorylation	LFVKFLETESHPSIP HHHHHHHCCCCCCCC	44.96	-
1882	Phosphorylation	SIPPPKLSVHDMKPL CCCCCCCCCCCCCCC	24.43	23403867
1891	Phosphorylation	HDMKPLDSPGRRKRD CCCCCCCCCCCCCCC	36.62	29255136
1904	Phosphorylation	RDTNAPESFKDTAES CCCCCCHHHHHCHHH	36.22	27251275
1917	Phosphorylation	ESRSGRRTDVNPFLA HHCCCCCCCCCCCCC	42.83	28555341

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TRIPB_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TRIPB_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TRIPB_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RB_HUMAN	RB1	physical	9256431
THA_HUMAN	THRA	physical	9256431
PRS8_HUMAN	PSMC5	physical	8603043
A16L1_HUMAN	ATG16L1	physical	27173435

Drug and Disease Associations

Kegg Disease
H00678	Achodrogenesis type IA
OMIM Disease
	Note=A chromosomal aberration involving TRIP11 may be a cause of acute myelogenous leukemia. Translocation t(5
	14)(q33
	q32) with PDGFRB. The fusion protein may be involved in clonal evolution of leukemia and eosinophilia.
200600
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TRIPB_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1842 AND THR-1846, ANDMASS SPECTROMETRY.	19690332 [Abstract]
"Lys-N and trypsin cover complementary parts of the phosphoproteome ina refined SCX-based approach."; Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J.,Mohammed S.; Anal. Chem. 81:4493-4501(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-486, AND MASSSPECTROMETRY.	19413330 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-464; SER-1842 ANDTHR-1846, AND MASS SPECTROMETRY.	18669648 [Abstract]
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