dbPTM

TRI55_RAT - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TRI55_RAT
UniProt AC	Q5PQN5
Protein Name	Tripartite motif-containing protein 55
Gene Name	Trim55
Organism	Rattus norvegicus (Rat).
Sequence Length	545
Subcellular Localization	Cytoplasm. Nucleus. Nuclear under atrophic conditions and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with microtubules.
Protein Description	May regulate gene expression and protein turnover in muscle cells..
Protein Sequence	MSTSLNYKSFSKEQQTMDNLEKQLICPICLEMFTKPVVILPCQHNLCRKCASDIFQASNPYLPTRGGTTVASGGRFRCPSCRHEVVLDRHGVYGLQRNLLVENIIDIYKQESTRPEKKLDQPMCEEHEEERINIYCLNCEVPTCSLCKVFGAHKDCQVAPLTHVFQRQKSELSDGIAVLVGSNDRVQGVISQLEDTCKTIEECCRKQKQDLCEKFDHLYSILEERKTEMTQAITRTQEEKLEHVRTLIRKYSDHLENVSKLVESGIQFMDEPEMAVFLQNAKTLLQKITEASKAFQMEKIEQGYEIMNNFTVNLNREEKIIREIDFSREEEDEDDEGEVDEEGEGEDAVEVEEAENVQVASSGEEETLEKAAEPSELAAEIQAASGPLLASSPDSVSSLPPAADVLVTQGEVVPTDSQQTTQSETSGPSAAETADPLFYPSWYKGQSRKMISNPPHTPGGEGLSQIGPSAAEDSSVQSAEVAEAAANEQAAVSGKESSSTAATSQIGFEASSPQGQAAALGSGGGADSEPARHVFSFSWLNSLNE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
170	Phosphorylation	HVFQRQKSELSDGIA HHHHHCHHCCCCCEE	35.12	22673903
173	Phosphorylation	QRQKSELSDGIAVLV HHCHHCCCCCEEEEE	29.73	22673903

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TRI55_RAT !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TRI55_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TRI55_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TRI55_RAT !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TRI55_RAT

Related Literatures of Post-Translational Modification