TREX2_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TREX2_MOUSE
• UniProt AC: Q9R1A9
• Protein Name: Three prime repair exonuclease 2
• Gene Name: Trex2
• Organism: Mus musculus (Mouse).
• Sequence Length: 236
• Subcellular Localization: Nucleus .
• Protein Description: Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair..
• Protein Sequence: MSEPPRAETFVFLDLEATGLPNMDPEIAEISLFAVHRSSLENPERDDSGSLVLPRVLDKLTLCMCPERPFTAKASEITGLSSESLMHCGKAGFNGAVVRTLQGFLSRQEGPICLVAHNGFDYDFPLLCTELQRLGAHLPQDTVCLDTLPALRGLDRAHSHGTRAQGRKSYSLASLFHRYFQAEPSAAHSAEGDVHTLLLIFLHRAPELLAWADEQARSWAHIEPMYVPPDGPSLEA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	SLFAVHRSSLENPER EEEEEEHHHCCCCCC	25.13	23832136
61	Phosphorylation	PRVLDKLTLCMCPER HHHHCCCEEEECCCC	24.53	-
71	Phosphorylation	MCPERPFTAKASEIT ECCCCCCCCCHHHHC	29.90	-
171	Phosphorylation	AQGRKSYSLASLFHR CCCCHHHHHHHHHHH	25.26	28507225

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TREX2_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TREX2_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TREX2_MOUSE !!

Protein-Protein Interaction

Oops, there are no PPI records of TREX2_MOUSE !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.