| UniProt ID | TR1L1_HUMAN | |
|---|---|---|
| UniProt AC | Q8N609 | |
| Protein Name | Translocating chain-associated membrane protein 1-like 1 | |
| Gene Name | TRAM1L1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 369 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein. |
|
| Protein Description | Stimulatory or required for the translocation of secretory proteins across the ER membrane.. | |
| Protein Sequence | MGLRKKSTKNPPVLSQEFILQNHADIVSCVGMFFLLGLVFEGTAEASIVFLTLQHSVAVPAAEEQATGSKSLYYYGVKDLATVFFYMLVAIIIHATIQEYVLDKINKRMQFTKAKQNKFNESGQFSVFYFFSCIWGTFILISENCLSDPTLIWKARPHSMMTFQMKFFYISQLAYWFHAFPELYFQKTKKQDIPRQLVYIGLHLFHITGAYLLYLNHLGLLLLVLHYFVELLSHMCGLFYFSDEKYQKGISLWAIVFILGRLVTLIVSVLTVGFHLAGSQNRNPDALTGNVNVLAAKIAVLSSSCTIQAYVTWNLITLWLQRWVEDSNIQASCMKKKRSRSSKKRTENGVGVETSNRVDCPPKRKEKSS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 7 | Phosphorylation | -MGLRKKSTKNPPVL -CCCCCCCCCCCCCC | 47.88 | 26670566 | |
| 8 | Phosphorylation | MGLRKKSTKNPPVLS CCCCCCCCCCCCCCC | 43.66 | 26670566 | |
| 107 | Acetylation | YVLDKINKRMQFTKA HHHHHHHHHHHHHHH | 53.36 | 11495535 | |
| 302 | Phosphorylation | AAKIAVLSSSCTIQA HHHHHHHCCCCEEHH | 17.38 | 24043423 | |
| 303 | Phosphorylation | AKIAVLSSSCTIQAY HHHHHHCCCCEEHHH | 25.85 | 24043423 | |
| 304 | Phosphorylation | KIAVLSSSCTIQAYV HHHHHCCCCEEHHHH | 16.35 | 24043423 | |
| 306 | Phosphorylation | AVLSSSCTIQAYVTW HHHCCCCEEHHHHHH | 20.33 | 24043423 | |
| 310 | Phosphorylation | SSCTIQAYVTWNLIT CCCEEHHHHHHHHHH | 5.09 | 24043423 | |
| 312 | Phosphorylation | CTIQAYVTWNLITLW CEEHHHHHHHHHHHH | 8.92 | 24043423 | |
| 332 | Phosphorylation | EDSNIQASCMKKKRS HCCCHHHHHCHHCCC | 9.81 | - | |
| 339 | Phosphorylation | SCMKKKRSRSSKKRT HHCHHCCCCCCCCCC | 45.45 | - | |
| 342 | Phosphorylation | KKKRSRSSKKRTENG HHCCCCCCCCCCCCC | 40.88 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of TR1L1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of TR1L1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of TR1L1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of TR1L1_HUMAN !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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