dbPTM

TPST_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TPST_ARATH
UniProt AC	Q3EDG5
Protein Name	Protein-tyrosine sulfotransferase
Gene Name	TPST
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	500
Subcellular Localization	Golgi apparatus membrane Single-pass type I membrane protein .
Protein Description	Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides..
Protein Sequence	MQMNSVWKLSLGLLLLSSVIGSFAELDFGHCETLVKKWADSSSSREEHVNKDKRSLKDLLFFLHVPRTGGRTYFHCFLRKLYDSSEECPRSYDKLHFNPRKEKCKLLATHDDYSLMAKLPRERTSVMTIVRDPIARVLSTYEFSVEVAARFLVHPNLTSASRMSSRIRKSNVISTLDIWPWKYLVPWMREDLFARRDARKLKEVVIIEDDNPYDMEEMLMPLHKYLDAPTAHDIIHNGATFQIAGLTNNSHLSEAHEVRHCVQKFKSLGESVLQVAKRRLDSMLYVGLTEEHRESASLFANVVGSQVLSQVVPSNATAKIKALKSEASVTISETGSDKSNIQNGTSEVTLNKAEAKSGNMTVKTLMEVYEGCITHLRKSQGTRRVNSLKRITPANFTRGTRTRVPKEVIQQIKSLNNLDVELYKYAKVIFAKEHELVSNKLISSSKRSIVDLPSELKSVLGEMGEEKLWKFVPVALMLLLIVLFFLFVNAKRRRTSKVKI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
156	N-linked_Glycosylation	ARFLVHPNLTSASRM HHHHHCCCCCCHHHH	40.86	-
248	N-linked_Glycosylation	FQIAGLTNNSHLSEA EEEECCCCCCCHHHH	53.72	-
271	Phosphorylation	KFKSLGESVLQVAKR HHHHHCHHHHHHHHH	26.74	19880383
315	N-linked_Glycosylation	LSQVVPSNATAKIKA HHHHCCCCHHHHHHH	34.93	-
343	N-linked_Glycosylation	SDKSNIQNGTSEVTL CCCCCCCCCCCEEEE	52.49	-
359	N-linked_Glycosylation	KAEAKSGNMTVKTLM HHHHHCCCCCHHHHH	30.00	-
395	N-linked_Glycosylation	LKRITPANFTRGTRT CCCCCCCCCCCCCCC	39.77	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TPST_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TPST_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TPST_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of TPST_ARATH !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TPST_ARATH

Related Literatures of Post-Translational Modification